Tanigaki Kenji

タニガキケンジ | Tanigaki Kenji

Affiliation and department：
Job title： Senior Scientist
Homepage URL (1)： https://www.pref.shiga.lg.jp/shigamed/divisions/neuron/index.html

Research field (1)： Medical biochemistry

Research keywords (10)： schizophrenia , 22q11 deletion syndrome , 包括脳ネットワーク , RBP-J , 神経発生 , conditional knockout , Notch , 大脳皮質 , 発生医学 , conditional knockout mice

Research theme for competitive and other funds (16)：

2023 - 2026 統合失調症発症に関与するエピスタシスの分子メカニズムの解明
2022 - 2025 難治性卵巣癌に対する、抗VEGF抗体とB7H3を標的とした併用療法の開発
2021 - 2025 Development of molecular-targeted anticancer agents for epigenetic changes in malignant glioma
2020 - 2023 Elucidation of the missing heritability of schizophrenia
2020 - 2023 Analysis of NOTCH and PROP1 as new therapeutic targets in high-risk pituitary adenomas

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Papers (53)：

Yoshito Sugita, Shigeki Takada, Kenji Tanigaki, Kazue Muraki, Munehiro Uemura, Masato Hojo, Susumu Miyamoto. Inhibition of VEGF receptors induces pituitary apoplexy: An experimental study in mice. PloS one. 2023. 18. 3. e0279634
Takeshi Hiramoto, Akira Sumiyoshi, Takahira Yamauchi, Kenji Tanigaki, Qian Shi, Gina Kang, Rie Ryoke, Hiroi Nonaka, Shingo Enomoto, Takeshi Izumi, et al. Tbx1, a gene encoded in 22q11.2 copy number variant, is a link between alterations in fimbria myelination and cognitive speed in mice. Molecular psychiatry. 2022. 27. 2. 929-938
Taito Miyamoto, Ryusuke Murakami, Junzo Hamanishi, Kenji Tanigaki, Yuko Hosoe, Nathan Mise, Shiro Takamatsu, Yuka Mise, Masayo Ukita, Mana Taki, et al. B7-H3 Suppresses Antitumor Immunity via the CCL2-CCR2-M2 Macrophage Axis and Contributes to Ovarian Cancer Progression. Cancer immunology research. 2022. 10. 1. 56-69
Risa Kato, Akihiro Machida, Kensaku Nomoto, Gina Kang, Takeshi Hiramoto, Kenji Tanigaki, Kazutaka Mogi, Noboru Hiroi, Takefumi Kikusui. Maternal approach behaviors toward neonatal calls are impaired by mother's experiences of raising pups with a risk gene variant for autism. Developmental psychobiology. 2021. 63. 1. 108-113
Akihiko Shiino, Yoshitomo Shirakashi, Manabu Ishida, Kenji Tanigaki. Machine learning of brain structural biomarkers for Alzheimer's disease (AD) diagnosis, prediction of disease progression, and amyloid beta deposition in the Japanese population. Alzheimer's & dementia (Amsterdam, Netherlands). 2021. 13. 1. e12246

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MISC (27)：

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Patents (2)：

Education (1)：

- 2001 京都大学大学院大学医学研究科分子医学 (医学博士)

Professional career (1)：

医学博士 (京都大学大学院大学)

Work history (5)：

2023/04 - 現在 Shiga Medical Center, Research Institute Clinical Research Institute Senior Scientist
2018/01 - 2023/03 Shiga Medical Center, Research Institute Senior Scientist
2005 - 2017/12 滋賀県立成人病センター(研究所) 研究員
2004 - 京都大学医化学第一助手
2003 - 京都大学医化学第一日本学術振興会特別研究員

Association Membership(s) (2)：

THE JAPAN NEUROSCIENCE SOCIETY , THE MOLECULAR BIOLOGY SOCIETY OF JAPAN

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