Rchr
J-GLOBAL ID：201101051074725295   Update date: Nov. 18, 2024

Sakurai Takashi

サクライ タカシ | Sakurai Takashi
Affiliation and department：
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About -


Homepage URL  (1)： http://pharmacology.sakura.ne.jp
Research field  (3)： Neuroscience - general ,  Neuroanatomy and physiology ,  Pharmacology
Research keywords  (9)： アルツハイマー病 ,  病態モデル ,  アミロイド ,  軸索輸送 ,  凝集体伝播 ,  カルシウムイオン ,  膜マイクロドメイン ,  脂質 ,  プロテオーム
Papers (116)：
  • Takashi Murayama, Yuya Otori, Nagomi Kurebayashi, Toshiko Yamazawa, Hideto Oyamada, Takashi Sakurai, Haruo Ogawa. Dual role of the S5 segment in type 1 ryanodine receptor channel gating. Communications Biology. 2024. 7. 1
  • Aya Ikeda, Hongrui Meng, Daisuke Taniguchi, Muneyo Mio, Manabu Funayama, Kenya Nishioka, Mari Yoshida, Yuanzhe Li, Hiroyo Yoshino, Tsuyoshi Inoshita, et al. CHCHD2 P14L, found in amyotrophic lateral sclerosis, exhibits cytoplasmic mislocalization and alters Ca2+ homeostasis. PNAS nexus. 2024. 3. 8. pgae319
  • Masato Komai, Yuka Noda, Atsuya Ikeda, Nanaka Kaneshiro, Yuji Kamikubo, Takashi Sakurai, Takashi Uehara, Nobumasa Takasugi. Nuclear SphK2/S1P signaling is a key regulator of ApoE production and Aβ uptake in astrocytes. Journal of Lipid Research. 2024
  • Ryosuke Ishida, Nagomi Kurebayashi, Hiroto Iinuma, Xi Zeng, Shuichi Mori, Masami Kodama, Takashi Murayama, Hiroyuki Masuno, Fumi Takeda, Masatoshi Kawahata, et al. A potent and selective cis-amide inhibitor of ryanodine receptor 2 as a candidate for cardiac arrhythmia treatment. European journal of medicinal chemistry. 2023. 262. 115910-115910
  • Atsushi Hori, Tomohiko Ai, Takashi Hato, Haruka Inaba, Kimie Tanaka, Shoichi Sato, Mizuho Okamoto, Yuna Horiuchi, Faith Jessica Paran, Yoko Tabe, et al. Carvedilol suppresses ryanodine receptor-dependent Ca2+bursts in human neurons bearingPSEN1variants found in early onset Alzheimer’s disease. 2023
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MISC (106)：
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Books (2)：
  • Co-immunoprecipitation Analysis of GPCR Complexes in the Central Nervous System
    Neuromethods, vol 144, Humana Press, New York, NY 2019
  • 疾病の回復を促進する薬
    放送大学教育振興会 2017 ISBN:9784595317224
Professional career (1)：
  • 医学博士 (東京大学)
Work history (6)：
  • 2016 - 現在 The Open University of Japan
  • 2006 - 現在 Juntendo University Faculty of Medicine
  • 2000 - 2006 理化学研究所 脳科学総合研究センター 研究員
  • 1998 - 2000 Dept Physiol, Tufts Univ Sch Med, Postdoc
  • 1990 - 2000 The University of Tokyo Faculty of Medicine
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Association Membership(s) (6)：
American Chemical Society ,  日本筋学会 ,  Society for Neuroscience ,  日本認知症学会 ,  日本神経科学学会 ,  日本薬理学会
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