kawaguchi shin-ya

Affiliation and department：
Homepage URL (1)： http://www.nb.biophys.kyoto-u.ac.jp/main.html

Research field (1)： Neuroscience - general

Research keywords (21)： long-term depression , action potential , 蛍光イメージング , シナプス可塑性 , axon , dendrite , 運動学習 , プルキンエ細胞 , パッチクランプ , シナプス前部 , 小脳 , 抑制性シナプス , シミュレーション , システム生物学 , 包括脳ネットワーク , CaMKII , 統合脳・分子脳科学 , GABA(A)受容体 , インテグリン , GABARAP , 微小管

Research theme for competitive and other funds (16)：

2025 - 2028 神経細胞の「かたち」が規定する局所情報演算とその可塑性
2025 - 2027 光でつなぐ培養神経回路の適応的情報処理
2022 - 2025 記憶を生み出す神経回路可塑性の光技術を駆使した理解
2022 - 2025 記憶を生み出す神経回路可塑性の光技術を駆使した理解
2022 - 2024 軸索終末の入力受容能の獲得による新規長期可塑性の分子機構

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Papers (36)：

Kei Furukawa, Shin-ya Kawaguchi. Coordinated regulation of timing and strength of synaptic outputs by adrenergic receptors through control of action potentials in Purkinje cells. Frontiers in Cellular Neuroscience. 2025
Ryota Iwase, Shin-ya Kawaguchi. Counteracting memories acquired in parallel by limited pairings in eyeblink conditioning. [bioRxiv]. 2025
Takuma Inoshita, Shin-ya Kawaguchi. Increased reluctant vesicles underlie synaptic depression by GPR55 in axon terminals of cerebellar Purkinje cells. eLife (reviewed preprint). 2025
Reo Higashi, Masato Morita, Shin-ya Kawaguchi. Cl- -dependent amplification of excitatory synaptic potentials at distal dendrites revealed by voltage imaging. Science Advances. 2024
Kei Furukawa, Takuma Inoshita, Shin-ya Kawaguchi. Graded control of Purkinje cell outputs by cAMP through opposing actions on axonal action potential and transmitter release. The Journal of Physiology. 2024

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MISC (12)：

Nobuhiro Nagasaki, Tomoo Hirano, Shin-ya Kawaguchi. alpha- and beta CaMKII regulate inhibitory synaptic plasticity oppositely in the cerebellum. NEUROSCIENCE RESEARCH. 2011. 71. E219-E219
Manami Yamashita, Shin-ya Kawaguchi, Tomoo Hirano. Presynaptic plasticity at parallel fiber-Purkinje cell synapses in mice lacking GluD2. NEUROSCIENCE RESEARCH. 2011. 71. E326-E326
Shin-ya Kawaguchi, Tomoo Hirano. Regulation of Inhibitory Synaptic Plasticity by Temporal Sequence of Ca2+ Signals in a Cerebellar Purkinje Neuron. NEUROSCIENCE RESEARCH. 2010. 68. E87-E87
Nobuhiro Nagasaki, Tomoo Hirano, Shin-ya Kawaguchi. Subunit composition of CaMKII is critical for inhibitory synaptic plasticity in the cerebellum. JOURNAL OF PHYSIOLOGICAL SCIENCES. 2010. 60. S83-S83
Nobuhiro Nagasaki, Tomoo Hirano, Shin-ya Kawaguchi. CaMKII subunit composition regulates inhibitory synaptic plasticity in the cerebellum. NEUROSCIENCE RESEARCH. 2009. 65. S82-S82

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Professional career (1)：

博士(理学) (京都大学)

Work history (5)：

2019/10 - 現在 Kyoto University Graduate School of Science
2017/04 - 2019/09 Kyoto University Office of Society-Academia Collaboration for Innovation
2012/04 - 2017/03 Doshisha University Graduate School of Brain Science Associate Professor
2007/04 - 2012/03 Kyoto University Graduate School of Science
2004/04 - 2007/03 Kyoto University Graduate School of Science

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