Research field (3):
Functional biochemistry
, Molecular biology
, Neuroscience - general
Research keywords (5):
線虫
, 化学物質有害性評価
, 毒性作用機序
, 行動
, cognitive function
Research theme for competitive and other funds (11):
2022 - 2025 Comprehensive understanding of avoidance behavior caused by environmental sensing
2019 - 2021 動物と微生物の相互作用による脳機能の調節機構
2019 - 2021 インスリン経路と脂質代謝経路の相互作用に基づく神経回路スイッチ機構の解明
2018 - 2021 多様な生命活動を支える機能的RNA制御ネットワークの確立
2014 - 2018 Molecular neural mechanisms for behavioral modulation by inter-individual communication
2013 - 2018 Discovery of new molecules involved in learning and memory and study of their mode of action
2015 - 高次神経機能の獲得に必要な遺伝子発現制御ネットワークの解明
2013 - 2014 Elucidation of temporal and spatial dynamics of the insulin signaling pathway during learning and memory
2011 - 2012 選択的スプライシングを介する神経細胞の個性獲得メカニズムの解析
2008 - 2012 A study on the molecular and neural mechanisms of chemotaxis and associative learning
2009 - 2010 Elucidation of a novel mechanism regulated by insulin signaling pathway in learning and memory
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Papers (21):
Masahiro Tomioka, Yusuke Umemura, Yutaro Ueoka, Risshun Chin, Keita Katae, Chihiro Uchiyama, Yasuaki Ike, Yuichi Iino. Antagonistic regulation of salt and sugar chemotaxis plasticity by a single chemosensory neuron in Caenorhabditis elegans. PLoS genetics. 2023. 19. 9. e1010637
Taoruo Huang, Kota Suzuki, Hirofumi Kunitomo, Masahiro Tomioka, Yuichi Iino. Multiple p38/JNK mitogen-activated protein kinase (MAPK) signaling pathways mediate salt chemotaxis learning in C. elegans. G3 (Bethesda, Md.). 2023. 13. 9
Du Cheng, James S Lee, Maximillian Brown, Margaret S Ebert, Patrick T McGrath, Masahiro Tomioka, Yuichi Iino, Cornelia I Bargmann. Insulin/IGF signaling regulates presynaptic glutamate release in aversive olfactory learning. Cell reports. 2022. 41. 8. 111685-111685
Yasuaki Ike, Masahiro Tomioka, Yuichi Iino. Involvement of HECT-type E3 ubiquitin ligase genes in salt chemotaxis learning in Caenorhabditis elegans. Genetics. 2022. 220. 4
Masahiro Tomioka, Moon Sun Jang, Yuichi Iino. DAF-2c signaling promotes taste avoidance after starvation in Caenorhabditis elegans by controlling distinct phospholipase C isozymes. Communications Biology. 2022. 5. 1
高橋伸一郎, 亀井宏泰, 富岡征大, 清家瞳, 永田晋治, 尾添淳文, 伯野史彦. Physiological Significance of Insulin-like Peptide System from Evolutionary Perspective: The Anabolic Hormone Responsible for the Lifelong Health of Animals. 化学と生物. 2022. 60. 5. 240-250
Functions of insulin-like peptide signaling in the C. elegans nervous system.
(Kick-off Symposium of “International Research on Regulation of Insulin-Like Activities for Extension of Health Life Span” 2021)
Gordon Research Conferences (IGF & Insulin System in Physiology & Disease)
(Gordon Research Conferences (IGF & Insulin System in Physiology & Disease) 2019)
2001 - 2006 University of Tokyo Graduate School of Science Department of Biophysics and Biochemistry
1997 - 2001 Tokyo Institute of Technology School of Bioscience and Biotechnology Department of Biological Sciences
Professional career (1):
博士(理学) (東京大学)
Work history (4):
2023 - 現在 National Institute of Occupational Safety and Health, Japan
2010 - 2023 The University of Tokyo Graduate School of Science
2007 - 2009 The University of Tokyo Graduate School of Science
2006 - 2007 The University of Tokyo Graduate School of Science
Association Membership(s) (6):
THE ZOOLOGICAL SOCIETY OF JAPAN
, Genetics Society of America
, THE RNA SOCIETY OF JAPAN
, Society for Neuroscience
, THE JAPAN NEUROSCIENCE SOCIETY
, THE MOLECULAR BIOLOGY SOCIETY OF JAPAN