Rchr
J-GLOBAL ID：201101057490961907   Update date: Apr. 25, 2024

Endo Shogo

エンドウ ショウゴ | Endo Shogo
Affiliation and department：
Tokyo Metropolitan Institute of Gerontology Aging Neuroscience Research Team

About Tokyo Metropolitan Institute of Gerontology Aging Neuroscience Research Team


Homepage URL  (1)： https://nrid.nii.ac.jp/nrid/1000060192514/
Research field  (2)： Nutrition and health science ,  Neuroscience - general
Research keywords  (23)： 基礎老年学 ,  老化 ,  Behavioral analysis ,  PDE ,  cAMP ,  ノックアウトマウス ,  プロテインホスファターゼ ,  Cre-LoxP ,  記憶学習 ,  Cre ,  MEK ,  ERK ,  G-substrate ,  MAPキナーゼ ,  cGMP ,  ERK2 ,  MAPK ,  LTD ,  プルキンエ細胞 ,  長期抑圧 ,  一酸化窒素 ,  遺伝子欠損マウス ,  小脳
Research theme for competitive and other funds  (17)：
  • 2024 - 2028 小脳と認知機能低下-加齢と脳内老廃物除去系の関与-
  • 2023 - 2025 Cognitive impairment viewed from the aging cerebellum
  • 2021 - 2023 Roles of 8-nitro-cGMP pathway as the coincident detector for memory formation.
  • 2019 - 2023 認知的フレイルとシグナル伝達機能低下ー早期発見から予防と克服へー
  • 2019 - 2021 Reactive oxygen species; physiological role in the brain
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Papers (103)：
  • Sho Kakizawa, Tomoko Arasaki, Ayano Yoshida, Ayami Sato, Yuka Takino, Akihito Ishigami, Takaaki Akaike, Shuichi Yanai, Shogo Endo. Essential role of ROS - 8-Nitro-cGMP signaling in long-term memory of motor learning and cerebellar synaptic plasticity. Redox Biology. 2024. 70. 103053-103053
  • Atsushi Sato, Yusuke Yumita, Kazuki Kagami, Yuki Ishinoda, Toyokazu Kimura, Ayumu Osaki, Takumi Toya, Takayuki Namba, Shogo Endo, Yasuo Ido, et al. Endothelial Extracellular Signal-Regulated Kinase/Thromboxane A2/Prostanoid Receptor Pathway Aggravates Endothelial Dysfunction and Insulin Resistance in a Mouse Model of Metabolic Syndrome. Journal of the American Heart Association. 2022. 11. 23. e027538
  • Shuichi Yanai, Tetsuro Tago, Jun Toyohara, Tomoko Arasaki, Shogo Endo. Reversal of spatial memory impairment by phosphodiesterase 3 inhibitor cilostazol is associated with reduced neuroinflammation and increased cerebral glucose uptake in aged male mice. Frontiers in pharmacology. 2022. 13. 1031637-1031637
  • Takehiko Kujiraoka, Kazuki Kagami, Toyokazu Kimura, Yuki Ishinoda, Yasunaga Shiraishi, Yasuo Ido, Shogo Endo, Yasushi Satoh, Takeshi Adachi. Metabolic Remodeling with Hepatosteatosis Induced Vascular Oxidative Stress in Hepatic ERK2 Deficiency Mice with High Fat Diets. International journal of molecular sciences. 2022. 23. 15
  • Tomoya Shintani, Shuichi Yanai, Akane Kanasaki, Misuzu Tanaka, Tetsuo Iida, Genki Ozawa, Tadao Kunihiro, Shogo Endo. Long-term D-Allose Administration Favorably Alters the Intestinal Environment in Aged Male Mice. Journal of applied glycoscience. 2022. 69. 4. 97-102
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MISC (103)：
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Patents (5)：
Lectures and oral presentations  (19)：
  • Attacking memory decline through the knowledge of signal transduction pathways
    (2015)
  • 東日本大震災が引き起こしたマウスの行動変化
    (第90回実験動物コンファレンス 2015)
  • 記憶改善薬のスクリーニングとSAM
    (第29回SAM研究協議会研究発表会 2014)
  • ドリッグリポジショニングを展望した認知症機能改善薬の前臨床スクリーニング
    (第3回TOBIRA研究フォーラム 2014)
  • Memory-enhanced mice provide clues to the treatment of memory impairments
    (29th Annual conference of Indian Academy of Neuroscience, 2011)
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Education (3)：
  • 1985 - 1988 Hokkaido University Faculty of Pharmaceutical Sciences
  • 1983 - 1985 Hokkaido University Faculty of Pharmaceutical Sciences
  • 1979 - 1983 Hokkaido University Faculty of Pharmaceutical Sciences
Professional career (1)：
  • 薬学博士 (北海道大学)
Work history (10)：
  • 2009 - 現在 Tokyo Metropolitan Institute of Gerontology Aging Neuroscience Research Team Team Leader
  • 2019 - 2022 芝浦工大 システム理工学部 客員教授
  • 2010 - 2020 Tokyo University of Agriculture and Technology
  • 2004 - 2009 沖縄科学技術研究基盤整備機構 記憶と学習の分子神経生物学ユニット ・代表研究者
  • 2000 - 2005 RIKEN Brain Science Institute, Endo Research Unit
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Committee career (7)：
  • 2021/04 - 現在 Japan Gerontological Society Executive Committee Member
  • 2021/04 - 現在 IAGG (International Association of Gerontology and Geriatrics) Councilor
  • 2021/04 - 2023/03 日本基礎老化学会 理事
  • 2017/04 - 2019/03 日本基礎老化学会 庶務理事
  • 2007/04 - 2010/03 沖縄県 科学技術会議、委員
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Association Membership(s) (5)：
American Society for Biochemistry and Molecular Biology ,  Society for Neuroscience ,  日本基礎老化学会 ,  日本分子生物学会 ,  日本神経科学学会
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