Sakai Yusuke

サカイユウスケ | Sakai Yusuke

Affiliation and department：
Job title： Associate Professor

Research field (4)： Biomedical engineering , Medical systems , General surgery, pediatric surgery , Applied biofunctional and bioprocess engineering

Research keywords (4)：再生医用工学 , 再生医工学 , Tissue engineering , 生物化学工学

Research theme for competitive and other funds (21)：

2024 - 2027 Development of extracellular matrix fiber composite multilayer monolith needle for diabetes treatment
2023 - 2025 多層モノリスニードルによる着脱可能な膵島細胞移植システムの創出
2021 - 2023 Fabrication of detachable-liver based on liver-derived ECM sponge needle
2020 - 2023 Fabrication of bioengineered sphincter construct with myoblast sheet
2020 - 2023 表在性非乳頭十二指腸腫瘍に対する内視鏡治療と腹腔鏡手術と再生医療を組み合わせた革新的な術式の開発

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Papers (60)：

Kengo Kanetaka, Yasuhiro Maruya, Miki Higashi, Shun Yamaguchi, Ryo Matsumoto, Shinichiro Kobayashi, Keiichi Hashiguchi, Fumiya Oohashi, Masaki Matsumura, Takahiro Naka, et al. A first-in-human clinical study of laparoscopic autologous myoblast sheet transplantation to prevent delayed perforation after duodenal endoscopic mucosal dissection. Stem Cell Research & Therapy. 2024. 15. 1
Yi Zhang, Jannatul Fardous, Yuuta Inoue, Ryota Doi, Asami Obata, Yusuke Sakai, Shinichi Aishima, Hiroyuki Ijima. Subcutaneous angiogenesis induced by transdermal delivery of gel-in-oil nanogel dispersion. Biomaterials Advances. 2023. 154
Hiroyuki Ijima, Yukako Fukuda, Mario Kokichi Uehara, Muhammad Shafiq, Fanqi Wu, Jaeyong Cho, Yusuke Sakai, Tatsunori Miyata, Takanobu Yamao, Yosuke Nakao, et al. Decellularized mouse liver as a small-scale scaffold for the creation of a miniaturized human liver. Journal of Chemical Engineering of Japan. 2023. 56. 1
Takayuki Miyoshi, Masaaki Hidaka, Daisuke Miyamoto, Yusuke Sakai, Shunsuke Murakami, Yu Huang, Takanobu Hara, Akihiko Soyama, Kengo Kanetaka, Takahiro Ochiya, et al. Successful induction of human chemically induced liver progenitors with small molecules from damaged liver. Journal of gastroenterology. 2022. 57. 6. 441-452
Yusuke Sakai, Yoshihiro Kubo, Nana Shirakigawa, Yoshinori Kawabe, Masamichi Kamihira, Hiroyuki Ijima. Promotion of cyst formation from a renal stem cell line using organ-specific extracellular matrix gel format culture system. Gels. 2022. 8. 5. 312-312

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MISC (21)：

堺裕輔. 8章バイオテクノロジー 8.3 メディカルテクノロジー. 化学工学. 2022. 86. 10
堺裕輔. 内皮細胞は肝内胆管を再構成する重要なピース. 化学工学会バイオ部会ニュースレター. 2022. 55. 23-24
堺裕輔. 8章バイオテクノロジー 8.3 メディカルテクノロジー. 化学工学. 2021. 85. 10. 540-541
堺裕輔. 肝臓はどこまで再現できるのか?. 化学工学会バイオ部会ニュースレター. 2021. 53. 21-22
堺裕輔. 細胞シートによる消化器の創傷治癒と機能性臓器の作製. MEMBRANE. 2018. 43. 2. 34-39

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Patents (7)：

培養組織及びその製造方法
シート状物貼付デバイス
肝前駆細胞を含む細胞集団を製造する方法
Cell culture instrument and cell culture method using the same
細胞培養器具及びこれを用いた細胞培養方法

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Lectures and oral presentations (15)：

Liver reconstruction for regenerative medical science
(8th Shanghai - Kyushu - Yeungnam (SKY) Symposium & 23rd International Symposium on Clean Technology 2024)
Liver reconstruction for regenerative medical science
(Japan-Croatia Joint Symposium on Chemical Engineering & Plasma Agriculture for Young Scientists Global Networking (JC-JSChEPA) 2024)
臓器培養への挑戦 ~工学と医学の立場から~
(第409回化学システム工学専攻公開セミナー(東京大学) 2024)
肝臓組織を育て続けた20年~工学と医学の立場から~
(第33回九州地区若手ケミカルエンジニア討論会 2023)
肝臓再構築に向けた研究と展望
(日本再生医療学会第1回秋季科学シンポジウム 2019)

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Education (1)：

2007 - 2010 The University of Kitakyushu Graduate School of Environmental Engineering

Professional career (2)：

Doctor (Engineering) (The University of Kitakyushu)
博士(医学) (長崎大学)

Work history (7)：

2023/01 - 現在 Kyushu University Faculty of Engineering, Department of Chemical Engineering
2019/04 - 2022/12 Kyushu University Faculty of Engineering, Department of Chemical Engineering
2018/04 - 2019/03 Nagasaki University Graduate School of Biomedical Sciences
2015/04 - 2018/03 Nagasaki University School of Medicine
2011/04 - 2015/03 Nagasaki University Graduate School of Biomedical Sciences

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Committee career (1)：

2022/11 - 現在日本再生医療学会代議員

Awards (4)：

2019/07 - 第1回細胞シート工学イノベーションフォーラムポスター賞奨励賞管腔構造を有するヒト肝細胞/内皮細胞索状組織作製技術の確立
2018/12 - 長崎大学鐘韻会平成30年度鐘韻賞 Time-dependent structural and functional characterization of subcutaneous human liver tissue 及び Controlled cell morphology and liver-specific function of engineered primary hepatocytes by fibroblast layer cell densities
2015/05 - ASGCT 18th Annual Meeting Outstanding poster presentation award Reconstruction of vascularized subcutaneous liver tissue for minimally invasive cell therapy
2006/09 - 化学工学会バイオ部会化学工学会第38回秋季大会バイオ部会優秀ポスター賞微細加工・表面化学修飾基板を用いた肝細胞スフェロイドアレイ

Association Membership(s) (4)：

日本バイオマテリアル学会 , THE JAPANESE SOCIETY FOR REGENERTIVE MEDICINE , 肝細胞研究会 , THE SOCIETY OF CHEMICAL ENGINEERS, JAPAN

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