Rchr
J-GLOBAL ID:201101065128692232
Update date: May. 21, 2024
Maeta Kazuhiro
マエタ カズヒロ | Maeta Kazuhiro
Affiliation and department:
Research field (3):
Molecular biology
, Fetal medicine/Pediatrics
, Neuroscience - general
Research keywords (3):
antisense oligonucleotide
, 筋萎縮性疾患
, Neurodegenerative disease
Research theme for competitive and other funds (2):
- 2021 - 2024 Myostatin antisense nucleic acid therapy for rhabdomyosarcoma
- 2007 - 2008 Reverse array analysis for post-translational modification of histones
Papers (36):
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Kazuhiro Maeta, Manal Farea, Hisahide Nishio, Masafumi Matsuo. A novel splice variant of the human MSTN gene encodes a myostatin-specific myostatin inhibitor. Journal of cachexia, sarcopenia and muscle. 2023
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Atsuhito Takeda, Masahiro Ueki, Jiro Abe, Kazuhiro Maeta, Tomoko Horiguchi, Hirokuni Yamazawa, Gaku Izumi, Ayako Chida-Nagai, Daisuke Sasaki, Takao Tsujioka, et al. A case of infantile Barth syndrome with severe heart failure: Importance of splicing variants in the TAZ gene. Molecular genetics & genomic medicine. 2023. 11. 7. e2190
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Toshihide Takeuchi, Kazuhiro Maeta, Xin Ding, Yukako Oe, Akiko Takeda, Mana Inoue, Seiichi Nagano, Tsuyoshi Fujihara, Seiji Matsuda, Shinsuke Ishigaki, et al. Sustained therapeutic benefits by transient reduction of TDP-43 using ENA-modified antisense oligonucleotides in ALS/FTD mice. Molecular therapy. Nucleic acids. 2023. 31. 353-366
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Kazuhiro Maeta, Manal Farea, Hisahide Nishio, Masafumi Matsuo. An Antisense Oligonucleotide against a Splicing Enhancer Sequence within Exon 1 of the MSTN Gene Inhibits Pre-mRNA Maturation to Act as a Novel Myostatin Inhibitor. International journal of molecular sciences. 2022. 23. 9
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Manal Farea, Kazuhiro Maeta, Hisahide Nishio, Masafumi Matsuo. Human Dystrophin Dp71ab Enhances the Proliferation of Myoblasts Across Species But Not Human Nonmyoblast Cells. Frontiers in cell and developmental biology. 2022. 10. 877612-877612
more...
MISC (2):
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Keisuke Okada, Koji Chiba, Teruo Fukuda, Noritoshi Enatsu, Kei Matsushita, Hideaki Miyake, Kazuhiro Maeta, Hironori Edamatsu, Toru Kataoka, Masato Fujisawa. LOSS OF RA-GEF-2 (RAPGEF6) IN MOUSE CAUSES ALTERED LOCALIZATION OF N-CADHERIN AND CAN CAUSE MALE INFERTILITY. JOURNAL OF UROLOGY. 2014. 191. 4. E741-E741
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K Maeta, S Izawa, Y Inoue. Activity of Yap1p transcription factor correlates with intracellular methylglyoxal level. YEAST. 2001. 18. S175-S175
Patents (5):
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TDP-43の発現量を調節するアンチセンスオリゴヌクレオチド及びその用途
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ミオスタチン遺伝子のmRNAの産生を抑制する核酸医薬
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アンギオテンシン変換酵素2遺伝子のエクソンのスキッピングを誘導するアンチセンス核酸
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ミオスタチンのスプライシングバリアントを発現させる核酸医薬
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ミオスタチンスプライスバリアント由来タンパク質によるミオスタチンシグナル阻害とその利用
Education (3):
- - 2005 京都大学大学院 農学研究科博士課程修了 (指導教員 井上善晴准教授)
- - 2002 京都大学大学院 農学研究科修士課程修了 (指導教員 井上善晴准教授)
- - 1999 Shimane University Faculty of Life and Environmental Science
Professional career (1):
Work history (9):
- 2023/04 - 現在 神戸学院大学 総合リハビリテーション学部 研究員
- 2018/07 - 現在 KNC Laboratories Co., Ltd
- 2018/07 - 2023/03 Faculty of Rehabilitation, Kobe Gakuin University
- 2017/01 - 2019/03 Nagoya Univ.
- 2016/07 - 2019/03 Osaka Univ.
- 2016/04 - 2016/06 Kobe Univ.
- 2011/10 - 2016/03 Kobe Univ.
- 2006/04 - 2011/09 RIKEN
- 2005/04 - 2006/03 Kyoto University Graduate School of Agriculture
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Association Membership(s) (5):
JAPANESE SOCIETY FOR CHEMICAL BIOLOGY
, THE JAPANESE BIOCHEMICAL SOCIETY
, 日本筋学会
, 日本人類遺伝学会
, 日本分子生物学会
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