HOSOI Nobutake

ホソイノブタケ | HOSOI Nobutake

Affiliation and department：

Research field (1)： Neuroscience - general

Research keywords (10)： image and movie analysis , animal behavior , retina , cerebellum , Ca imaging , Patchclamp , Electrophysiology , Neuroscience , シナプス伝達 , 包括脳ネットワーク

Research theme for competitive and other funds (8)：

2023 - 2026 Development of microglia-targeting AAV vectors and its application to neurodegenerative disorders
2020 - 2023 発達における短期シナプス可塑性の切換えメカニズム
2018 - 2022 Epigenetic modulation by chemical substances on thyroid hormone-mediated brain development.
2017 - 2022 Mechanism of activity-dependent motor improvement in SCA
2016 - 2018 Development of gene therapy against neurodegenerative diseases using CRISPR/Cas9-based genome editing

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Papers (22)：

Sotaro Ichinose, Yoshihiro Susuki, Nobutake Hosoi, Ryosuke Kaneko, Mizuho Ebihara, Hirokazu Hirai, Hirohide Iwasaki. Interaction between Teneurin-2 and microtubules via EB proteins provides a platform for GABAA receptor exocytosis. eLife. 2023. 12
二ノ宮彩音, 天野出月, 小久保倫文, 高鶴裕介, 石井角保, 平井宏和, 細井延武, 鯉淵典之. 変異甲状腺ホルモン受容体を発現させたマウスプルキンエ細胞では、長期抑圧誘発刺激は長期増強を惹起する. 日本内分泌学会雑誌. 2023. 99. 1. 286-286
Yukihiro Okada, Nobutake Hosoi, Yasunori Matsuzaki, Yuuki Fukai, Akito Hiraga, Junichi Nakai, Keisuke Nitta, Yoichiro Shinohara, Ayumu Konno, Hirokazu Hirai. Development of microglia-targeting adeno-associated viral vectors as tools to study microglial behavior in vivo. Communications Biology. 2022. 5. 1
Ayane Ninomiya, Izuki Amano, Michifumi Kokubo, Yusuke Takatsuru, Sumiyasu Ishii, Hirokazu Hirai, Nobutake Hosoi, Noriyuki Koibuchi. Long-term depression-inductive stimulation causes long-term potentiation in mouse Purkinje cells with a mutant thyroid hormone receptor. Proceedings of the National Academy of Sciences of the United States of America. 2022. 119. 45. e2210645119
二ノ宮彩音, Abdallah Mshaty, はい島旭, 矢島弘之, 小久保倫文, Aghnia Khairinisa Miski, Ariyani Winda, 藤原悠基, 石井角保, 細井延武, et al. 授乳期PFOS曝露による小脳機能の発達異常の体系的解析. 日本内分泌学会雑誌. 2022. 98. 3. 707-707

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MISC (11)：

Hosoi Nobutake. Elucidating the Mechanisms of Life using Patchclamp Technique and Live Imaging. The Kitakanto Medical Journal. 2023. 73. 3. 225-226
二ノ宮彩音, 細井延武, 天野出月, 小久保倫文, 高鶴裕介, 平井宏和, 鯉淵典之. 小脳機能維持における甲状腺ホルモンの新たな役割の解明プルキンエ細胞小胞体からのカルシウム放出調節における重要性. 日本内分泌学会雑誌. 2021. 97. 1. 265-265
Nobutake Hosoi, Hirokazu Hirai. Genetically-modified diseased mice and cerebellar abnormalities. 2021. 72. 1. 69-73
定方哲史, 細井延武, 柴崎貢志, 今野歩, 平井宏和, 石崎泰樹, 古市貞一. クラスIIARFタンパク質は、小脳プルキンエ細胞の軸索起始部へのNav1.6チャネルの輸送に関与する. 日本生化学会大会プログラム・講演要旨集. 2019. 92回. [1T14a-01]
定方哲史, 細井延武, 柴崎貢志, 今野歩, 平井宏和, 石崎泰樹, 古市貞一. クラスIIARFタンパク質は、小脳プルキンエ細胞の軸索起始部へのNav1.6チャネルの輸送に関与する. 日本生化学会大会プログラム・講演要旨集. 2019. 92回. [1T14a-01]

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Work history (4)：

2020/11 - 現在 Gunma University Graduate School of Medicine Department of Neurophysiology and Neural Repair Associate Professor
2015/06 - 2020/10 Gunma University Graduate School of Medicine Department of Neurophysiology and Neural Repair
2009/04 - 2015/05 Gunma University Graduate School of Medicine Department of Neurophysiology Assisrant professor
2004/04 - 2009/03 Max Planck Institute for Biohysical Chemistry Department of Membrane Biophysics (Erwin Neher lab) Postdoctoral fellow

Association Membership(s) (4)：

SOCIETY for NEUROSCIENCE , THE ZOOLOGICAL SOCIETY OF JAPAN , THE PHYSIOLOGICAL SOCIETY OF JAPAN , THE JAPAN NEUROSCIENCE SOCIETY

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