Hashimoto Kouichi

Affiliation and department：

Research field (1)： Neuroscience - general

Research keywords (21)：包括脳ネットワーク , 統合脳・分子脳科学 , critical period , NMDA受容体 , 生後発達 , シナプス除去 , 多重支配 , 神経活動 , 神経科学 , IP3受容体 , シグナル伝達 , Gene Gun , 脳神経 , リアノジン受容体 , シナプス , 代謝型グルタミン酸受容体 , 平行線維 , 発達 , 登上線維 , 小脳 , プルキンエ細胞

Research theme for competitive and other funds (9)：

2017 - 2021 Functional roles of the electrical activity in postnatal refinement of the neuronal circuitry
2018 - 2020 延髄下オリーブ核閾値下膜電位オシレーションの分子機構と機能的意義の解明
2016 - 2018 Molecular mechanisms for the resonant property of neurons
2015 - 2018 Project to create international glial researcher network: mainly focusing on Japan-Germany research exchange
2015 - 2018 Basic research on elucidation of neurocircuit pathology of depression and its remodeling mechanism

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Papers (69)：

Hisako Nakayama, Taisuke Miyazaki, Manabu Abe, Maya Yamazaki, Yoshinobu Kawamura, Myeongjeong Choo, Kohtarou Konno, Shinya Kawata, Naofumi Uesaka, Kouichi Hashimoto, et al. Direct and indirect pathways for heterosynaptic interaction underlying developmental synapse elimination in the mouse cerebellum. Communications biology. 2024. 7. 1. 806-806
Reika Kubo, Takayuki Yoshida, Kenji Yamaoka, Kouichi Hashimoto. The indirect cortico-pontine pathway relays perioral sensory signals to the cerebellum via the mesodiencephalic junction. iScience. 2023. 107301-107301
Yuto Okuno, Kazuto Sakoori, Kyoko Matsuyama, Miwako Yamasaki, Masahiko Watanabe, Kouichi Hashimoto, Takaki Watanabe, Masanobu Kano. PTPδ is a presynaptic organizer for the formation and maintenance of climbing fiber to Purkinje cell synapses in the developing cerebellum. Frontiers in Molecular Neuroscience. 2023. 16
Kana Okada, Kouichi Hashimoto, Kazuto Kobayashi. Cholinergic regulation of object recognition memory. Frontiers in Behavioral Neuroscience. 2022. 16. 996089
Kazue Hisaoka-Nakashima, Kazuto Ohata, Natsuki Yoshimoto, Shintarou Tokuda, Nanako Yoshii, Yoki Nakamura, Dengli Wang, Keyue Liu, Hidenori Wake, Takayuki Yoshida, et al. High-mobility group box 1-mediated hippocampal microglial activation induces cognitive impairment in mice with neuropathic pain. EXPERIMENTAL NEUROLOGY. 2022. 355

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MISC (6)：

久保怜香, 橋本浩一. Sensory signal transduction pathways from the perioral area to the cerebellar Purkinje cells. 生体の科学. 2021. 72. 1
久保怜香, 饗場篤, 橋本浩一. マウスヒゲ触覚信号はarea parafascicularis prerubralisから下オリーブ核への経路を経て小脳に伝達される. 日本生理学雑誌(Web). 2019. 81. 2
橋本浩一, 辻田実加, 喜多村和郎, 宮崎太輔, 山崎真弥, Shin Hee-Sup, 渡辺雅彦, 崎村建司, 狩野方伸. 小脳回路発達と可塑性の最前線登上線維の発達過程におけるP/Q型電位依存性カルシウムチャネルの役割(Cellebellar circuitry: Cutting-edge of development and plasticity P/Q type voltage dependent Ca2+ channel is crucial for early postnatal development of climbing fiber to Purkinje cell synapse). 神経化学. 2010. 49. 2-3. 461-461
橋本浩一. 発達期小脳における登上線維-プルキンエ細胞シナプスの機能分化. 日本生理学雜誌 = JOURNAL OF THE PHYSIOLOGICAL SOCIETY OF JAPAN. 2003. 65. 11
井ノ口馨, 橋本浩一, 真鍋俊也, 畑裕, 溝口明, 高橋正身, 狩野方伸. 遺伝子制御による選択的シナプス強化・除去機構の解明 (文部科学省S). 科学技術振興調整費試験研究実施計画. 2001. 2001

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Professional career (1)：

Work history (10)：

2012/04 - 現在 Graduate School of Biomedical and Health Sciences, Hiroshima University Department of Neurophysiology Professor
2010/07 - 広島大学医歯薬学総合研究科教授
2008/04 - 2010/06 東京大学医学系研究科准教授
2005 - 2006 大阪大学医学系研究科助手
2006 - 大阪大学医学(系)研究科(研究院) 助手

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