Rchr
J-GLOBAL ID：201101083527736837
Update date: Feb. 01, 2024
Kenji Tanaka
タナカ ケンジ | Kenji Tanaka
Affiliation and department：
Job title：
Professor
Homepage URL (1)：
http://psy-keiomed-ect.com/index.html
Research field (1)：
Neuroscience - general
Research keywords (7)：
ventral striatum
, ventral hippocampus
, motivation
, optogenetics
, fiberphotometry
, KENGE-tet
, FASTシステム
Research theme for competitive and other funds (34)：
- 2020 - 2025 グリア・神経ネットワークの統合による脳内エネルギー代謝機構
- 2020 - 2025 Glia decoding: deciphering information critical for brain-body interactions
- 2018 - 2022 Establishment and applications of model mice with fluctuated deafness by advanced gene-engineering methods
- 2019 - 2021 意欲行動の持続にかかわる神経基盤の解明
- 2017 - 2020 Investigation of role of serotonergic neurons in regulation of masseter muscle activity using optogenetics
- 2018 - 2019 グリアアセンブリによる脳機能発現の制御と病態
- 2017 - 2019 負に立ち向かうウィルパワーをつかさどる神経基盤の解明
- 2016 - 2019 Understanding a role of cerebral angiogenesis and hyperemia on cognitive decline
- 2015 - 2019 Regulatory role of BDNF on emotional and cognitive function
- 2016 - 2018 The experimental attempt for brain evolution by increase of neurons in mouse cerebral cortex
- 2016 - 2018 線条体におけるカルシウム振動の描出と生理学的意義の解明
- 2015 - 2018 Project to create international glial researcher network: mainly focusing on Japan-Germany research exchange
- 2015 - 2018 Estimation of neural activity propagation pathway in the brain by applying deep learning
- 2015 - 2018 Control of stria vascularis function and changes of auditory and vestibular function induced by optogenetic stimulation
- 2015 - 2018 How does the cerebellum work during cognitive and emotional tasks?
- 2015 - 2018 Screening and analysis of glial factors for neuroprotection
- 2014 - 2018 A role of astrocyte in neuro-glio-vascular unit concerning cerebral microcirculation
- 2013 - 2018 Studies on communication between neuroaxons via oligodendrocytes.
- 2014 - 2017 Visualization and quantification of fluxes of glucose metabolic pathways in brain
- 2014 - 2017 Analysis of cerebral blood flow regulation using in vivo fluorescence imaging
- 2014 - 2017 Transcriptional repressor RP58 as neuronal maturation and maintenance
- 2013 - 2017 Testing serotonin hypothesis of depression with optogenetics
- 2013 - 2016 Investigation of brain-wide responses evoked by optogenetic activation of the dorsal or ventral hippocampus
- 2010 - 2016 Comprehensive Brain Science Network
- 2013 - 2015 うつ病における神経回路変容の抽出と解析
- 2011 - 2015 Oligodendrocyte-neuron interaction
- 2012 - 2014 グリア細胞操作を起点とする神経活動変化と伝播様式解析
- 2012 - 2014 The interaction between serotonergic and cannabinoidergic neurotransmissions in the basolateral amygdala
- 2012 - 2014 Development of animal model enabling the manipulation of intracellular Ca level
- 2011 - 2014 Study for neural mechanism of wakefulness and dependence using optogenetics
- 2011 - 2014 Localization of excitatory and inhibitory astrocytes, and their generation mechanism
- 2009 - 2010 光分子センサー・メラノプシンの神経細胞種依存的な活性化機構のモーダルシフトと応用
- 2009 - 2010 Analysis of astrocytic function by using STOP-tetO system
- 2003 - 2007 ニューロン-グリア相互作用に関与する機能分子の探索
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Papers (202)：
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Takashi Komori, Kazuya Okamura, Minobu Ikehara, Kazuhiko Yamamuro, Nozomi Endo, Kazuki Okumura, Takahira Yamauchi, Daisuke Ikawa, Noriko Ouji-Sageshima, Michihiro Toritsuka, et al. Brain-derived neurotrophic factor from microglia regulates neuronal development in the medial prefrontal cortex and its associated social behavior. Molecular Psychiatry. 2024
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Abe Y, Erchinger VJ, Ousdal OT, Oltedal L, Tanaka KF, Takamiya A. Neurobiological mechanisms of electroconvulsive therapy for depression: Insights into hippocampal volumetric increases from clinical and preclinical studies. Journal of Neurochemistry. 2024
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Yoshifumi Abe, Sho Yagishita, Hiromi Sano, Yuki Sugiura, Masanori Dantsuji, Toru Suzuki, Ayako Mochizuki, Daisuke Yoshimaru, Junichi Hata, Mami Matsumoto, et al. Shared GABA transmission pathology in dopamine agonist- and antagonist-induced dyskinesia. Cell reports. Medicine. 2023. 4. 10. 101208-101208
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Takahito Uchida, Yuki Sugiura, Eiji Sugiyama, Rae Maeda, Kenji F Tanaka, Makoto Suematsu, Masaru Mimura, Hiroyuki Uchida. Metabolites for monitoring symptoms and predicting remission in patients with depression who received electroconvulsive therapy: a pilot study. Scientific reports. 2023. 13. 1. 13218-13218
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Akihiro Takamiya, Yoshifumi Abe, Kiichi Yokoyama, Tomonobu Kato, Sho Yagishita, Kenji Tanaka. Neurogenesis-independent mechanisms of MRI-detectable hippocampal volume increase following electroconvulsive stimulation. 2023
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MISC (159)：
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田中 謙二. アパシーの成因・治療を考える アパシーの脳内基盤 リバーストランスレーショナル研究. 老年精神医学雑誌. 2021. 32. 増刊I. 177-177
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松瀬 大, 山口 浩雄, 眞崎 勝久, 西村 由宇慈, 田中 辰典, 雑賀 徹, 田中 謙二, 山崎 亮, 吉良 潤一, 磯部 紀子. 新規小脳型多系統萎縮症モデルのCSF-1R阻害剤治療. パーキンソン病・運動障害疾患コングレスプログラム・抄録集. 2021. 15回. 92-92
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松瀬 大, 山口 浩雄, 眞崎 勝久, 西村 由宇慈, 田中 辰典, 雑賀 徹, 田中 謙二, 山崎 亮, 吉良 潤一. オリゴデンドロサイト特異的αシヌクレイン蓄積による小脳型多系統萎縮症モデルの樹立. パーキンソン病・運動障害疾患コングレスプログラム・抄録集. 2021. 14回. 110-110
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木村 範子, 河野 佐代子, 滝上 紘之, 山市 大輔, 片山 奈理子, 竹内 啓善, 菊地 俊暁, 佐渡 充洋, 内田 裕之, 田中 謙二, et al. COVID-19こころのケアチーム活動報告. 総合病院精神医学. 2020. 32. Suppl. S-193
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田中 謙二, 阿部 欣史, 權 秀珍, 大石 光洋. 新しい役者を標的にした脳卒中研究の新潮流-グリア細胞、神経幹細胞、血管壁細胞- 血管壁細胞の光操作. 脳循環代謝. 2020. 32. 1. 54-54
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Lectures and oral presentations (47)：
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the 5th BRI International Symposium: Genome editing technology; its status quo and application to brain research
(the 5th BRI International Symposium: Genome editing technology; its status quo and application to brain research 2015)
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特定細胞集団の活動を操作する、観察する
(都医学研セミナー 2015)
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第25回マイクロダイアリシス研究会
(第25回マイクロダイアリシス研究会 2014)
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精神医学研究にオプトジェネティクスが期待されること
(第35回日本レーザー医学会総会 2014)
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Microglia transform astrocytes into neuroprotective phenotypes by inhibiting P2Y1 receptors.
(第57回日本神経化学会大会 2014)
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Works (2)：
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ゆとりの時間「Let's Enjoy High School Science」
田中謙二 2013 - 現在
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夏休みの研究体験
2013 - 2013
Professional career (2)：
- 博士(医学) (慶應義塾)
- Doctor (Medicine) (Keio University)
Work history (5)：
- 2016/01 - 現在 Keio University School of Medicine
- 2012 - 2015/12 慶應義塾大学医学部 精神神経科 特任准教授
- 2006 - 2008 Columbia University
- 2008 - National Institute for Physiological Sciences
- 2005 - National Institute for Physiological Sciences Department of Molecular Physiology
Association Membership(s) (2)：
日本精神神経学会
, THE JAPANESE SOCIETY FOR NEUROCHEMISTRY
