Ono Daisuke

オノダイスケ | Ono Daisuke

Affiliation and department：
Homepage URL (1)： https://daiono14.wixsite.com/circadianrhythm

Research field (3)： Animals: biochemistry, physiology, behavioral science , Neuroscience - general , Physiology

Research keywords (17)：環境適応 , 動物行動 , 光操作 , 神経回路 , 発達 , 視床下部 , 睡眠 , ニューロン , 脳 , 包括脳ネットワーク , イメージング , 同期現象 , 生物発光 , 視交叉上核 , 概日リズム , 神経科学 , 生理学

Research theme for competitive and other funds (14)：

2021 - 2025 胎生期における超早期脳ゲノム編集治療法の開発
2022 - 2024 Understanding of the regulation of sleep and wakefulness by CRF neurons in mice
2021 - 2024 概日時計による体温調節メカニズムの解明
2020 - 2024 Understanding of sleep-wake regulatory mechanisms in nature
2022 - 2024 厳しい地球環境に適応するための哺乳類生体機能の解明

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Papers (45)：

Pham XT, Abe Y, Mukai Y, Ono D, Tanaka KF, Ohmura Y, Wake H, Yamanaka A. Glutamatergic signaling from melanin-concentrating hormone-producing neurons: A requirement for memory regulation, but not for metabolism control. PNAS Nexus. 2024. 3. 7
Hiroto Ito, Noriaki Fukatsu, Sheikh Mizanur Rahaman, Yasutaka Mukai, Shuntaro Izawa, Daisuke Ono, Thomas S. Kilduff, Akihiro Yamanaka. Deficiency of orexin signaling during sleep is involved in abnormal REM sleep architecture in narcolepsy. Proceedings of the National Academy of Sciences. 2023. 120. 41
Yasutaka Mukai, Tatsuo S. Okubo, Michael Lazarus, Daisuke Ono, Kenji F. Tanaka, Akihiro Yamanaka. Prostaglandin E₂Induces Long-Lasting Inhibition of Noradrenergic Neurons in the Locus Coeruleus and Moderates the Behavioral Response to Stressors. The Journal of Neuroscience. 2023. 43. 47. 7982-7999
Daisuke Ono, Huan Wang, Chi Jung Hung, Hsin-Tzu Wang, Naohiro Kon, Akihiro Yamanaka, Yulong Li, Takashi Sugiyama. Network-driven intracellular cAMP coordinates circadian rhythm in the suprachiasmatic nucleus. Science advances. 2023. 9. 1. eabq7032
Apirada Padlom, Daisuke Ono, Rio Hamashima, Yuko Furukawa, Takashi Yoshimura, Taeko Nishiwaki-Ohkawa. Level of constitutively expressed BMAL1 affects the robustness of circadian oscillations. Scientific reports. 2022. 12. 1. 19519-19519

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MISC (12)：

Circadian clock and postnatal development. 2016. 67. 6. 550-554
Honma S, Ono D, Enoki R, Yoshikawa T, Kuroda S, Honma K. Oscillator networks in the suprachiasmatic nucleus: analysis of circadian parameters using time-laps images. Biological Clocks - 30th Anniversary of Sapporo Symposium on Biological Rhythm, (eds by Honma K and Honma S). 2016. 33-41
Shin-ya Nishide, Yoko Suzuki, Daisuke Ono, Ken-ichi Honma, Sato Honma, Serge Daan. Hypothermia is induced by restricted feeding in mice : Effect of time of day. JOURNAL OF PHYSIOLOGICAL SCIENCES. 2013. 63. S259-S259
Ryosuke Enoki, Shigeru Kuroda, Daisuke Ono, Hasan Mazahir, Tetsuo Ueda, Sato Honma, Ken-ichi Honma. Large-Scale Circadian Calcium Imaging in Neuronal Network of the Suprachiasmatic Nucleus. JOURNAL OF PHYSIOLOGICAL SCIENCES. 2013. 63. S53-S53
MURAKAMI Akitoshi, HIROTA Sinya, TAKEUCHI Akimasa, INOUE Kousuke, ONO Daisuke, HONMA Sato, KOTANI Kiyoshi, JIMBO Yasuhiko. Functional characterization of suprachiasmatic nucleus cultured with retina. 2012. 2012. 34. 21-24

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Lectures and oral presentations (27)：

Circadian regulation of sleep and wakefulness in mammals
(2nd Japanese-Canadian Frontiers of Science (JCFoS) symposium 2020)
GABA in the suprachiasmatic nucleus refines circadian behavioral rhythms
(V World Congress of Chronobiology 2019)
The brain mechanism of circadian clock.
(3rd ITCN, Taipei 2019)
概日時計が調節する睡眠覚醒の神経回路
(第3回ルミノジェネティクス研究会 2018)
Postnatal development of cellular networks in the mammalian central circadian clock
(2018)

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Professional career (1)：

Work history (8)：

2020/10 - 現在名古屋大学環境医学研究所講師
2016/10 - 2020/09 Nagoya University Research Institute of Environmental Medicine
2016/04 - 2016/09 Nagoya University Research Institute of Environmental Medicine
2013/04 - 2016/03 Hokkaido University Graduate School of Medicine
2012/04 - 2013/03 Hokkaido University Graduate School of Medicine

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Awards (5)：

Association Membership(s) (4)：

THE JAPAN NEUROSCIENCE SOCIETY , PHYSIOLOGICAL SOCIETY OF JAPAN , 日本時間生物学会 , Society for Research on Biological Rhythms (SRBR)

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