Uchigashima Motokazu

Affiliation and department：

Research field (2)： Neuroscience - general , Neuroanatomy and physiology

Research keywords (7)：分子イメージング , Neurotransmission , Synaptic cell adhesion molecules , Endocannabinoid , Monoamine , Striatum , 包括脳ネットワーク

Research theme for competitive and other funds (11)：

2020 - 2025 Inducing lifelong plasticity (iPlasticity) by brain rejuvenation: elucidation and manipulation of critical period mechanisms
2020 - 2025 Analysis of Molecular Dynamics for Structural Spine Plasticity during the Critical Period
2020 - 2023 線条体中型有棘ニューロンにおけるドーパミン伝達の時空間的統合過程の理解
2020 - 2022 Development of a novel method for analyzing the distribution of endogenous proteins in mammalian brain tissues
2020 - 2020 ドーパミンシナプスの生細胞イメージングを介したドーパミン神経伝達の理解

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Papers (57)：

Kenjiro Hanaoka, Shimpei Iwaki, Kiyoshi Yagi, Takuya Myochin, Takayuki Ikeno, Hisashi Ohno, Eita Sasaki, Toru Komatsu, Tasuku Ueno, Motokazu Uchigashima, et al. General Design Strategy to Precisely Control the Emission of Fluorophores via a Twisted Intramolecular Charge Transfer (TICT) Process. Journal of the American Chemical Society. 2022. 144. 43. 19778-19790
Motokazu Uchigashima, Amy Cheung, Kensuke Futai. Neuroligin-3: A Circuit-Specific Synapse Organizer That Shapes Normal Function and Autism Spectrum Disorder-Associated Dysfunction. Frontiers in Molecular Neuroscience. 2021. 14. 749164-749164
Motokazu Uchigashima, Kohtarou Konno, Emily Demchak, Amy Cheung, Takuya Watanabe, David G Keener, Manabu Abe, Timmy Le, Kenji Sakimura, Toshikuni Sasaoka, et al. Specific Neuroligin3-αNeurexin1 signaling regulates GABAergic synaptic function in mouse hippocampus. eLife. 2020. 9
Ryoji Fukabori, Yoshio Iguchi, Shigeki Kato, Kazumi Takahashi, Satoshi Eifuku, Shingo Tsuji, Akihiro Hazama, Motokazu Uchigashima, Masahiko Watanabe, Hiroshi Mizuma, et al. Enhanced Retrieval of Taste Associative Memory by Chemogenetic Activation of Locus Coeruleus Norepinephrine Neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2020. 40. 43. 8367-8385
Motokazu Uchigashima, Ming Leung, Takuya Watanabe, Amy Cheung, Timmy Le, Sabine Pallat, Alexandre Luis Marques Dinis, Masahiko Watanabe, Yuka Imamura Kawasawa, Kensuke Futai. Neuroligin3 splice isoforms shape inhibitory synaptic function in the mouse hippocampus. The Journal of biological chemistry. 2020. 295. 25. 8589-8595

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MISC (20)：

井口善生, 深堀良二, 加藤成樹, 高橋和巳, 永福智志, 辻真伍, 挾間章博, 内ヶ島基政, 渡辺雅彦, 水間広, et al. 青斑核ノルアドレナリン神経細胞の活動亢進による情動記憶の想起の促進新規神経活動活性化ツールによる検討. 日本生理学雑誌. 2021. 83. 2. 39-39
Fukabori, R, Iguchi, Y, Kato, S, Takahashi, K, Eifuku, S, Tsuji, S, Hazama, A, Uchigashima, M, Watanabe, M, Mizuma, H, et al. Enhanced emotional memory retrieval by chemogenetic activation of locus coeruleus norepinephrine neurons. Mendeley Data. 2019
M. Kano, M. Narushima, M. Uchigashima, M. Watanabe, A. Aiba, M. Miyata. Requirement of mGluR1 for Experience-Dependent Remodeling of Mouse Retinogeniculate Synapses. CURRENT NEUROPHARMACOLOGY. 2014. 12. 30-31
Lack of Molecular-Anatomical Evidence for GABAergic Influence on Axon Initial Segment of Cerebellar Purkinje Cells by the Pinceau Formation. 2012. 87. 6. 273-273
Unique inhibitory synapse with particularly rich endocannabinoid signaling machinery on pyramidal neurons in basal amygdaloid nucleus. 2012. 87. 2. 72-72

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Professional career (1)：

博士(医学) (北海道大学)

Work history (6)：

2021/10 - 現在 International Research Center for Neurointelligence, The University of Tokyo Institutes for Advanced Study Affiliated Faculty
2019/03 - 現在 Niigata University Brain Research Institute
2017/04 - 2019/02 Hokkaido University
2016/02 - 2018/03 University of Massachusetts Medical School Brudnick Neuropsychiatric Research Institute Visiting Scholar
2011/04 - 2017/03 Hokkaido University Graduate School of Medicine

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Awards (12)：

2022/09 - 新潟大学新潟大学学長賞(若手教員研究奨励)
2022/02 - 北海道大学医学部同窓会フラテ研究奨励賞
2021/12 - 新潟大学新潟大学優秀論文表彰
2021/08 - 新潟大学新潟大学学長賞
2020/12 - 北海道大学医学部エクセレントティーチャー優秀賞

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