Rchr
J-GLOBAL ID：201101099913149931   Update date: Feb. 01, 2024

Masuda Yuichi

マスダ ユウイチ | Masuda Yuichi
Affiliation and department：
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About -


Homepage URL  (1)： http://www.cc.mie-u.ac.jp/~masuda/
Research field  (2)： Pharmaceuticals - chemistry and drug development ,  Bioorganic chemistry
Research keywords  (5)： conformation analysis ,  cyclic peptide ,  Nuclear Magnetic Resonance ,  Peptide Chemistry ,  Bioorganic Chemistry
Research theme for competitive and other funds  (7)：
  • 2019 - 2022 Elucidation of 3D structure and target molecule-recognition mechanism of hypeptin, an antimicrobial cyclic peptide.
  • 2016 - 2019 生物活性環状ペプチドPF1171類の生体内における立体配座解明と標的分子同定
  • 2017 - 2018 PF1171ペンタペプチドとヘキサペプチドに共通するファーマコフォアの解明
  • 2014 - 2016 環状ペプチドPF1171類の三次元構造に着目した活性発現機構研究
  • 2012 - 2014 アミロイドβの毒性発現に係わるメチオニンラジカルの硫黄33固体NMRによる研究
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Papers (39)：
  • Yuichi Masuda, Shinobu Ohki, Yuuki Mogami, Kenzo Deguchi, Kenjiro Hashi, Atsushi Goto, Tadashi Shimizu, Kazuhiko Yamada. Solution and solid-state 33 S NMR studies of 33 S-labeled taurine. Magnetic resonance in chemistry : MRC. 2023. 61. 11. 589-594
  • Takayuki Doi, Kosuke Ohsawa, Yuichi Masuda. Cyclic Tetrapeptide Natural Product Asperterrestide A: Total Synthesis and Structural Revision. Journal of Synthetic Organic Chemistry, Japan. 2023. 81. 6. 554-561
  • Kazuhiko Yamada, Yuichi Masuda. A sulfur-33 nuclear quadrupole resonance study of S-33(2)-labeled L-cystine. MAGNETIC RESONANCE IN CHEMISTRY. 2023. 61. 5. 296-300
  • Masaya Honda, Minoru Inagaki, Yuichi Masuda. Total synthesis of the cyclic pentapeptides PF1171B, D, E, and avellanins A, B, C with inhibitory activity against apolipoprotein B production. TETRAHEDRON LETTERS. 2021. 81. 153340
  • Yuka Yoshida, Minoru Inagaki, Yuichi Masuda. Solid-phase synthesis and bioactivity evaluation of cherimolacyclopeptide E. JOURNAL OF PEPTIDE SCIENCE. 2021. 27. 6
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MISC (37)：
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Patents (3)：
  • アミロイドβの凝集体の測定方法
  • 環状デプシペプチド化合物
  • Antibody recognizing turn structure in amyloid beta.
Lectures and oral presentations  (42)：
  • NMR analysis of hydrogen bonds in PF1171F, a cyclic hexapeptide with insecticidal activity, under pseudo body’s internal environment.
    (第56回ペプチド討論会 2019)
  • Elucidation of important 3D structures for bioactivity of naturally occurring peptides.
    (23rd Korean Peptide and Protein Society Symposium 2019)
  • 3D Structure-activity relationship study of naturally occurring peptides and its application to drug design.
    (10th International Peptide Symposium 2018)
  • 環状ペプチドの三次元構造に基づくドラッグデザイン
    (技術情報協会セミナー:環状ペプチドの創製・構造解析とライブラリの開発~ペプチドミメティックを活用した中分子創薬~ 2018)
  • 環状ペプチドPF1171Fの生体内環境における立体配座のNMRによる解析
    (日本農芸化学会2018年度大会 2018)
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Education (2)：
  • 2004 - 2009 Kyoto University Graduate School of Agriculture Division of Food Science and Biotechnology
  • 2000 - 2004 Kyoto University Faculty of Agriculture
Professional career (1)：
  • 博士(農学) (京都大学)
Work history (4)：
  • 2016/01 - 現在 Graduate School of Bioresources, Mie University Laboratory of Medicinal Chemistry Associate Professor
  • 2015/04 - 2016/12 Graduate School of Pharmaceutical Sciences, Tohoku University Laboratory of Heterocyclic Chemistry Research Fellow
  • 2011/05 - 2015/03 Graduate School of Pharmaceutical Sciences, Tohoku University Laboratory of Heterocyclic Chemistry Assistant Professor
  • 2009/04 - 2011/04 Department of Chemistry , Graduate School of Science, Kyoto University JSPS Research Fellow
Awards (5)：
  • 2020/03 - 日本農芸化学会 2020年度農芸化学奨励賞
  • 2018/12 - 日本ペプチド学会 平成30年度日本ペプチド学会 奨励賞
  • 2015/03 - 日本農芸化学会 2015年度大会トピックス賞
  • 2009/03 - 日本農芸化学会 2008年度 B.B.B. 論文賞
  • 2008/10 - 日本ペプチド学会 第45回ペプチド討論会 若手口頭発表優秀賞
Association Membership(s) (4)：
THE SOCIETY OF SYNTHETIC ORGANIC CHEMISTRY, JAPAN ,  THE PHARMACEUTICAL SOCIETY OF JAPAN ,  日本ペプチド学会 ,  日本農芸化学会
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