Art

J-GLOBAL ID：201102200015531290   Reference number：11A1158034

A pipeline that integrates the discovery and verification of plasma protein biomarkers reveals candidate markers for cardiovascular disease

血漿タンパク質バイオマーカーの探索と検証を統合するパイプラインによって心血管疾患のマーカー候補を明らかにする

Author (20)： ADDONA Terri A (Broad Inst. of MIT and Harvard, Massachusetts, USA) ,  KESHISHIAN Hasmik (Broad Inst. of MIT and Harvard, Massachusetts, USA) ,  MANI D R (Broad Inst. of MIT and Harvard, Massachusetts, USA) ,  BURGESS Michael (Broad Inst. of MIT and Harvard, Massachusetts, USA) ,  GILLETTE Michael A (Broad Inst. of MIT and Harvard, Massachusetts, USA) ,  CLAUSER Karl R (Broad Inst. of MIT and Harvard, Massachusetts, USA) ,  GERSZTEN Robert E (Broad Inst. of MIT and Harvard, Massachusetts, USA) ,  CARR Steven A (Broad Inst. of MIT and Harvard, Massachusetts, USA) ,  SHI Xu (Massachusetts General Hospital, Massachusetts, USA) ,  SHEN Dongxiao (Massachusetts General Hospital, Massachusetts, USA) ,  LEWIS Gregory D (Massachusetts General Hospital, Massachusetts, USA) ,  FARRELL Laurie A (Massachusetts General Hospital, Massachusetts, USA) ,  FIFER Michael A (Massachusetts General Hospital, Massachusetts, USA) ,  SABATINE Marc S (Massachusetts General Hospital, Massachusetts, USA) ,  GERSZTEN Robert E (Massachusetts General Hospital, Massachusetts, USA) ,  GILLETTE Michael A (Massachusetts General Hospital, Massachusetts, USA) ,  LEWIS Gregory D (Donald W. Reynolds Cardiovascular Clinical Res. Center on Atherosclerosis at Harvard Medical School, Massachusetts, USA) ,  SABATINE Marc S (Donald W. Reynolds Cardiovascular Clinical Res. Center on Atherosclerosis at Harvard Medical School, Massachusetts, USA) ,  GERSZTEN Robert E (Donald W. Reynolds Cardiovascular Clinical Res. Center on Atherosclerosis at Harvard Medical School, Massachusetts, USA) ,  SABATINE Marc S (Brigham and Women’s Hospital, Massachusetts, USA)
Material： Nature Biotechnology  (Nat Biotechnol)
Volume： 29  Issue： 7  Page： 635-643  Publication year： Jul. 2011 
JST Material Number： H0870A  ISSN： 1087-0156  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Thesaurus term： *plasma protein ,  *biomarker ,  *screening(inspection) ,  pipeline arithmetic ,  *hypertrophic cardiomyopathy ,  LC-MS analysis ,  *proteomics ,  *blood examination
Semi thesaurus term： LC-MS/MS analysis ,  *心血管バイオマーカー ,  *精密適用マス・スクリーニング

JST classification (3)： Cardiovascular system diagnosis  (GJ02000V) ,  Blood tests(=hematologic tests)  (GC02050D) ,  Mass spectrometry  (CC03013N)

Terms in the title (8)： 血漿タンパク質 ,  バイオマーカー ,  探索 ,  検証 ,  統合 ,  パイプライン ,  心血管疾患 ,  マーカー