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J-GLOBAL ID：201102204061347199   Reference number：11A1836489

Factors Predicting Outcome in Stroke Patients Treated With 0.6 mg/kg Alteplase: Evidence From the Japan Alteplase Clinical Trial (J-ACT)

0.6mg/kgのアルテプラーゼで治療した脳卒中患者の転帰を予測する因子 日本アルテプラーゼ臨床試験(J-ACT)からの証拠

Author (4)： MORI Etsuro (Dep. of Behavioral Neurology and Cognitive Neuroscience, Tohoku Univ. Graduate School of Medicine, Sendai, JPN) ,  MINEMATSU Kazuo (Cerebrovascular Div., National Cardiovascular Center, Suita, JPN) ,  NAKAGAWARA Jyoji (Dep. of Neurosurgery and Stroke Center, Nakamura Memorial Hospital, Sapporo, JPN) ,  YAMAGUCHI Takenori (National Cardiovascular Center, Suita, JPN)
Material： Journal of Stroke & Cerebrovascular Diseases  (J Stroke Cerebrovasc Dis)
Volume： 20  Issue： 6  Page： 517-522  Publication year： Nov. 2011 
JST Material Number： W1420A  ISSN： 1052-3057  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Thesaurus term： human ,...
Semi thesaurus term： acute ischemic stroke ,...

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JST classification (2)： Clinical application of drugs acting on blood and body fluid  (GW14020X) ,  Drug therapy(=pharmacotherapy)for nervous system diseases  (GN05020Y)

Reference (20)：

• Yamaguchi T, Mori E, Minematsu K, et al. Japan Alteplase Clinical Trial (J-ACT) Group. Alteplase at 0.6 mg/kg for acute ischemic stroke within 3 hours of onset: Japan Alteplase Clinical Trial (J-ACT). Stroke 2006; 37: 1810-1815.
• National Institute of Neurological Disorders and Stroke rt-PA Stroke Study Group. Tissue plasminogen activator for acute ischemic stroke. N Engl J Med 1995; 333: 1581-1587.
• NINDS t-PA Stroke Study Group. Generalized efficacy of t-PA for acute stroke: Subgroup analysis of the NINDS t-PA Stroke Trial. Stroke 1997; 28: 2119-2125.
• Zangerle A, Kiechl S, Spiegel M, et al. Recanalization after thrombolysis in stroke patients: Predictors and prognostic implications. Neurology 2007; 68: 39-44.
• Molina CA, Alexandrov AV, Demchuk AM, et al. CLOTBUST Investigators. Improving the predictive accuracy of recanalization on stroke outcome in patients treated with tissue plasminogen activator. Stroke 2004; 35: 151-157.

Terms in the title (10)： アルテプラーゼ ,  治療 ,  脳卒中患者 ,  転帰 ,  予測 ,  因子 ,  日本 ,  臨床試験 ,  ACT ,  証拠