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J-GLOBAL ID：201102210804664577   Reference number：11A1614940

Overexpression of fatty acid synthase in human urinary bladder cancer and combined expression of the synthase and Ki-67 as a predictor of prognosis of cancer patients

ヒト膀胱癌における脂肪酸シンターゼの過剰発現と癌患者の予後予測因子としてのこのシンターゼとKi-67の共発現

Author (6)： SUGINO Takashi (Fukushima Medical Univ. School of Medicine, Fukushima, JPN) ,  BABA Keiichi (Fukushima Medical Univ. School of Medicine, Fukushima, JPN) ,  HOSHI Nobuo (Fukushima Medical Univ. School of Medicine, Fukushima, JPN) ,  AIKAWA Ken (Fukushima Medical Univ. School of Medicine, Fukushima, JPN) ,  YAMAGUCHI Osamu (Fukushima Medical Univ. School of Medicine, Fukushima, JPN) ,  SUZUKI Toshimitsu (Fukushima Medical Univ. School of Medicine, Fukushima, JPN)
Material： Medical Molecular Morphology  (Med Mol Morphol)
Volume： 44  Issue： 3  Page： 146-150  Publication year： Sep. 2011 
JST Material Number： L1883A  ISSN： 1860-1480  Document type： Article
Article type： 原著論文  Country of issue： Germany, Federal Republic of (DEU)  Language： ENGLISH (EN)

Thesaurus term： human ,...
Semi thesaurus term： *Ki-67 ,...

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JST classification (2)： Chemistry,biochemistry and pathology of tumors(=neoplasms)  (GE02030N) ,  Urogenital tumors(=neoplasms)  (GM04000S)

Reference (26)：

• WAKIL, SJ. Fatty acid synthase, a proficient multifunctional enzyme. Biochemistry. 1989, 28, 4523-4530
• KUSAKABE, T. Fatty acid synthase is highly expressed in carcinoma, adenoma and in regenerative epithelium and intestinal metaplasia of the stomach. Histopathology (Oxf). 2002, 40, 71-79
• RASHID, A. Elevation of fatty acid synthase expression and fatty acid synthetic activity in colorectal neoplasia. Am J Pathol. 1997, 150, 201-220
• PIYATHILAKE, CJ. The expression of fatty acid synthase (FASE) is an early event in the development and progression of squamous cell carcinoma of the lung. Hum Pathol. 2000, 31, 1068-1073
• NEMOTO, T. Overexpression of fatty acid synthase in esophageal dysplasia and carcinoma. Pathobiology. 2001, 69, 297-303

Terms in the title (9)： ヒト ,  膀胱癌 ,  脂肪酸シンターゼ ,  過剰発現 ,  癌患者 ,  予後予測因子 ,  シンターゼ ,  Ki-67 ,  共発現