Art

J-GLOBAL ID：201102215308064960   Reference number：11A0666874

An environmental contaminant, benzo(a)pyrene, induces oxidative stress-mediated interleukin-8 production in human keratinocytes via the aryl hydrocarbon receptor signaling pathway

環境汚染物質,ベンゾ(a)ピレンはヒトケラチノサイトでアリール炭化水素受容体シグナル経路を介して酸化ストレス誘発インターロイキン8の産生を誘導する

Author (10)： TSUJI Gaku (Dep. of Dermatology, Graduate School of Medical Sciences, Kyushu Univ., Fukuoka, JPN) ,  TAKAHARA Masakazu (Dep. of Dermatology, Graduate School of Medical Sciences, Kyushu Univ., Fukuoka, JPN) ,  UCHI Hiroshi (Dep. of Dermatology, Graduate School of Medical Sciences, Kyushu Univ., Fukuoka, JPN) ,  UCHI Hiroshi (Res. and Clinical Center for Yusho and Dioxin, Kyushu Univ. Hospital, Fukuoka, JPN) ,  TAKEUCHI Satoshi (Dep. of Dermatology, Graduate School of Medical Sciences, Kyushu Univ., Fukuoka, JPN) ,  MITOMA Chikage (Dep. of Dermatology, Graduate School of Medical Sciences, Kyushu Univ., Fukuoka, JPN) ,  MITOMA Chikage (Res. and Clinical Center for Yusho and Dioxin, Kyushu Univ. Hospital, Fukuoka, JPN) ,  MOROI Yoichi (Dep. of Dermatology, Graduate School of Medical Sciences, Kyushu Univ., Fukuoka, JPN) ,  FURUE Masutaka (Dep. of Dermatology, Graduate School of Medical Sciences, Kyushu Univ., Fukuoka, JPN) ,  FURUE Masutaka (Res. and Clinical Center for Yusho and Dioxin, Kyushu Univ. Hospital, Fukuoka, JPN)
Material： Journal of Dermatological Science  (J Dermatol Sci)
Volume： 62  Issue： 1  Page： 42-49  Publication year： Apr. 2011 
JST Material Number： W1280A  ISSN： 0923-1811  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Thesaurus term： pollutant ,...
Semi thesaurus term： cutaneous inflammatory disease

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JST classification (2)： Basic dermatology  (GF01020Y) ,  Other pollutants  (SB05040W)

Substance index (1)： Benzo(a)pyrene

Reference (55)：

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• CHEN, SC. Health risk assessment on humans exposed to environmental polycyclic aromatic hydrocarbons pollution sources. Sci Total Environ. 2006, 366, 112-123
• BAGDON, RE. Skin permeation and cutaneous hypersensitivity as a basis for making risk assessments of chromium as a soil contaminant. Environ Health Perspect. 1991, 92, 111-119
• NEBERT, DW. Role of aryl hydrocarbon receptor mediated induction of the CYP1 enzymes in environmental toxicity and cancer. J Biol Chem. 2004, 279, 23847-23850
• MANDAL, PK. Dioxin : a review of its environmental effects and its aryl hydrocarbon receptor biology. J Comp Physiol B. 2005, 175, 221-230

Terms in the title (10)： 環境汚染物質 ,  ピレン ,  ヒト ,  ケラチノサイト ,  アリール炭化水素受容体 ,  シグナル経路 ,  酸化ストレス ,  誘発 ,  インターロイキン8 ,  誘導