Art

J-GLOBAL ID：201102221967008431   Reference number：11A1955435

Prevention of allergic asthma by vaccination with transgenic rice seed expressing mite allergen: induction of allergen-specific oral tolerance without bystander suppression

ダニアレルゲンを発現するトランスジェニックイネ種子を用いた予防接種によるアレルギー喘息の予防 バイスタンダー抑制のないアレルゲン特異的経口免疫寛容

Author (17)： SUZUKI Kazuya (National Inst. of Agrobiological Sci., Ibaraki, JPN) ,  SUZUKI Kazuya (Tokyo Metropolitan Inst. of Medical Sci., Tokyo, JPN) ,  KAMINUMA Osamu (Tokyo Metropolitan Inst. of Medical Sci., Tokyo, JPN) ,  YANG Lijun (National Inst. of Agrobiological Sci., Ibaraki, JPN) ,  TAKAI Toshiro (Juntendo Univ. School of Medicine, Tokyo, JPN) ,  MORI Akio (Sagamihara National Hospital, Kanagawa, JPN) ,  UMEZU-GOTO Makiko (Sagamihara National Hospital, Kanagawa, JPN) ,  OHTOMO Takayuki (Sagamihara National Hospital, Kanagawa, JPN) ,  OHMACHI Yasushi (National Inst. of Radiological Sci., Chiba, JPN) ,  NODA Yuko (National Inst. of Radiological Sci., Chiba, JPN) ,  HIROSE Sakiko (National Inst. of Agrobiological Sci., Ibaraki, JPN) ,  OKUMURA Ko (Juntendo Univ. School of Medicine, Tokyo, JPN) ,  OGAWA Hideoki (Juntendo Univ. School of Medicine, Tokyo, JPN) ,  TAKADA Kazuko (Nihon Univ. School of Dentistry at Matsudo, Chiba, JPN) ,  HIRASAWA Masatomo (Nihon Univ. School of Dentistry at Matsudo, Chiba, JPN) ,  HIROI Takachika (Tokyo Metropolitan Inst. of Medical Sci., Tokyo, JPN) ,  TAKAIWA Fumio (National Inst. of Agrobiological Sci., Ibaraki, JPN)
Material： Plant Biotechnology Journal  (Plant Biotechnol J)
Volume： 9  Issue： 9  Page： 982-990  Publication year： Dec. 2011 
JST Material Number： W1741A  ISSN： 1467-7644  Document type： Article
Article type： 原著論文  Country of issue： United Kingdom (GBR)  Language： ENGLISH (EN)

Thesaurus term： *allergen ,  Acarina ,  *Oryza sativa ,  *transgenic plant ,  seed ,  Vaccination ,  allergic disease ,  *asthma ,  *desensitization therapy ,  immunological tolerance ,  oral absorption ,  Immunity ,  Mus musculus ,  Serum ,  immunoglobulin ,  Cell Proliferation ,  ratio ,  helper T cell ,  cytokine ,  Inflammation ,  air duct (respiration) ,  cell migration ,  bronchial asthma ,  Lung ,  Biology ,  oral administration ,  Proteins ,  Eosinophils ,  Neutrophils ,  monocyte ,  egg albumin ,  immunoglobulin E ,  immunoglobulin G ,  gene expression ,  property ,  antigen recognition ,  cell infiltration ,  T cell ,  Th2 cytokine ,  T cell proliferation ,  *mite allergen ,  *transgenic rice ,  inflammatory cell infiltration ,  oral immunological tolerance ,  antigen specificity ,  Histology ,  lung tissue ,  immune response ,  CD4-Positive T-Lymphocytes ,  Th1-Th2 Balance ,  invertebrate ,  *organism ,  reaction ,  suppression and control ,  Myomorpha ,  molecular genetic phenomenon
Semi thesaurus term： immunological reaction ,  T lymphocyte ,  CD4+ T-cell ,  immunoglobulin E ,  IgG ,  TH1/TH2 ,  *Allergic asthma ,  *Allergen specific immunotherapy ,  ovalbumin ,  Bronchial Hyperreactivity ,  Airway inflammation ,  mononuclear cell

JST classification (6)： Antigens,antibodies,complements in general  (ED04010A) ,  Gene manipulation  (EC02050B) ,  Rice cropping  (FC03020C) ,  Basic research of immunotherapeutic agents and blood preparations  (GW22010D) ,  Respiratory system diseases  (GI03000Z) ,  Immunological reaction in general  (ED03010T)

Terms in the title (8)： ダニアレルゲン ,  発現 ,  イネ種子 ,  予防接種 ,  アレルギー喘息 ,  予防 ,  アレルゲン ,  経口免疫寛容