Art

J-GLOBAL ID：201102224181076270   Reference number：11A1930198

Oral Ingestion of Lentinula Edodes Mycelia (LEM) Mitigates Immunosuppression in Tumor-Bearing Hosts and Enhances an Effect of Anti-Cancer Peptide Vaccine

がんペプチドワクチン療法の進歩と課題 シイタケ菌糸体抽出物の経口摂取による担癌での免疫抑制解除と抗癌ペプチドワクチン効果の増強

Author (3)： TANAKA KOSUKE (小林製薬 中研) ,  MATSUI YASUNORI (小林製薬 中研) ,  HARADA MAMORU (島根大 医 免疫学)
Material： Biotherapy (Tokyo)  (日本バイオセラピィ学会学術集会総会プログラム・抄録集)
Volume： 25  Issue： 6  Page： 863-870  Publication year： Nov. 30, 2011 
JST Material Number： L0028A  ISSN： 0914-2223  Document type： Article
Article type： 文献レビュー  Country of issue： Japan (JPN)  Language： JAPANESE (JA)

Thesaurus term： *tumor vaccine ,...
Semi thesaurus term： *cancer vaccination therapy ,...

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JST classification (3)： Basic research of immunotherapeutic agents and blood preparations  (GW22010D) ,  Experimental treatment for tumors  (GE02040Y) ,  Basic research of pharmacology of crude drugs  (GX06020J)

Reference (17)：

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• 3) Robert, C., Thomas, L., Bondarenko, I., et al.: Ipilimumab plus dacarbazine for previously untreated metastatic melanoma. N. Engl. J. Med. 364 (26): 2517-2526,2011.
• 4) Itoh, A., Isoda, K., Kondoh, M., el al.: flepatopro-tective effect of syringic acid and vanillic acid on concanavalin a-induced liver injury. Biol. Pharm. Bull. 32(7): 1215-1219,2009.
• 5) Kojima, IL, Akaki, J., Nakajima, S., et al.: Struc-tural analysis of glycogen-like polysaccharides having macrophage-activating activity in extracts of Lentinula edodes mycelia. J. Nal. Med. 64 (1): 16-23,2010.

Terms in the title (7)： がん ,  ペプチドワクチン療法 ,  シイタケ菌糸体抽出物 ,  経口摂取 ,  免疫抑制 ,  癌ペプチドワクチン ,  増強