Art

J-GLOBAL ID：201102225036094941   Reference number：11A1080421

Transgenic rescue of desmoglein 3 null mice with desmoglein 1 to develop a syngeneic mouse model for pemphigus vulgaris

尋常天疱瘡の同系マウスモデルを開発するためのデスモグレイン1によるデスモグレイン3ヌルマウスのトランスジェニック救援

Author (10)： HATA Tsuyoshi (Dep. of Dermatology, Keio Univ. School of Medicine, Tokyo, JPN) ,  HATA Tsuyoshi (Cutaneous Res. Section, Fundamental Res. Laboratories, KOSE Corp., Tokyo, JPN) ,  NISHIFUJI Koji (Dep. of Dermatology, Keio Univ. School of Medicine, Tokyo, JPN) ,  SHIMODA Kouji (Dep. of Lab. Animal Center, Keio Univ. School of Medicine, Tokyo, JPN) ,  SASAKI Takashi (Dep. of Dermatology, Keio Univ. School of Medicine, Tokyo, JPN) ,  SASAKI Takashi (Dep. of Center for Integrated Medical Res., Keio Univ. School of Medicine, Tokyo, JPN) ,  YAMADA Taketo (Dep. of Pathology, Keio Univ. School of Medicine, Tokyo, JPN) ,  NISHIKAWA Takeji (Dep. of Dermatology, Keio Univ. School of Medicine, Tokyo, JPN) ,  KOYASU Shigeo (Dep. of Microbiology and Immunology, Keio Univ. School of Medicine, Tokyo, JPN) ,  AMAGAI Masayuki (Dep. of Dermatology, Keio Univ. School of Medicine, Tokyo, JPN)
Material： Journal of Dermatological Science  (J Dermatol Sci)
Volume： 63  Issue： 1  Page： 33-39  Publication year： Jul. 2011 
JST Material Number： W1280A  ISSN： 0923-1811  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Thesaurus term： autoimmunity ,...
Semi thesaurus term： *Pemphigus vulgaris ,...

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JST classification (4)： Basic dermatology  (GF01020Y) ,  Molecular genetics in general  (EC02010J) ,  Immunological reaction in general  (ED03010T) ,  Immunologic diseases,allergic diseases in general.  (GD04010C)

Reference (28)：

• STANLEY, JR. Pemphigus and pemphigoid as paradigms of organ-specific, autoantibody-mediated diseases. J Clin Invest. 1989, 83, 1443-1448
• AMAGAI, M. Pemphigus vulgaris antigen (desmoglein 3) is localized in the lower epidermis, the site of blister formation in patients. J Invest Dermatol. 1996, 106, 351-355
• AMAGAI, M. Autoantibodies against a novel epithelial cadherin in pemphigus vulgaris, a disease of cell adhesion. Cell. 1991, 67, 869-877
• ANHALT, GJ. Induction of pemphigus in neonatal mice by passive transfer of IgG from patients with the disease. N Engl J Med. 1982, 306, 1189-1196
• AMAGAI, M. Autoantibodies against the amino-terminal cadherin-like binding domain of pemphigus vulgaris antigen are pathogenic. J Clin Invest. 1992, 90, 919-926

Terms in the title (6)： 尋常天疱瘡 ,  マウスモデル ,  開発 ,  デスモグレイン1 ,  デスモグレイン3 ,  救援