Art

J-GLOBAL ID：201102226731494396   Reference number：11A0793312

A rare variant in MYH6 is associated with high risk of sick sinus syndrome

MYH6のまれな変異は洞不全症候群の高いリスクに関連する

Author (34)： HOLM Hilma (deCODE genetics, Reykjavik, ISL) ,  GUDBJARTSSON Daniel F (deCODE genetics, Reykjavik, ISL) ,  SULEM Patrick (deCODE genetics, Reykjavik, ISL) ,  MASSON Gisli (deCODE genetics, Reykjavik, ISL) ,  HELGADOTTIR Hafdis Th (deCODE genetics, Reykjavik, ISL) ,  ZANON Carlo (deCODE genetics, Reykjavik, ISL) ,  MAGNUSSON Olafur Th (deCODE genetics, Reykjavik, ISL) ,  HELGASON Agnar (deCODE genetics, Reykjavik, ISL) ,  SAEMUNDSDOTTIR Jona (deCODE genetics, Reykjavik, ISL) ,  GYLFASON Arnaldur (deCODE genetics, Reykjavik, ISL) ,  GRETARSDOTTIR Solveig (deCODE genetics, Reykjavik, ISL) ,  JONASDOTTIR Aslaug (deCODE genetics, Reykjavik, ISL) ,  SIGURDSSON Asgeir (deCODE genetics, Reykjavik, ISL) ,  STEFANSSON Hreinn (deCODE genetics, Reykjavik, ISL) ,  RAFNAR Thorunn (deCODE genetics, Reykjavik, ISL) ,  THORLEIFSSON Gudmar (deCODE genetics, Reykjavik, ISL) ,  WALTERS G Bragi (deCODE genetics, Reykjavik, ISL) ,  KONG Augustine (deCODE genetics, Reykjavik, ISL) ,  THORSTEINSDOTTIR Unnur (deCODE genetics, Reykjavik, ISL) ,  STEFANSSON Kari (deCODE genetics, Reykjavik, ISL) ,  STEFANSDOTTIR Hrafnhildur (Landspitali Univ. Hospital, Reykjavik, ISL) ,  THORGEIRSSON Gudmundur (Landspitali Univ. Hospital, Reykjavik, ISL) ,  ARNAR David O (Landspitali Univ. Hospital, Reykjavik, ISL) ,  MATTHIASSON Stefan E (Medical Clinics, Reykjavik, ISL) ,  THORGEIRSSON Gudmundur (Univ. Iceland, Reykjavik, ISL) ,  THORSTEINSDOTTIR Unnur (Univ. Iceland, Reykjavik, ISL) ,  ARNAR David O (Univ. Iceland, Reykjavik, ISL) ,  STEFANSSON Kari (Univ. Iceland, Reykjavik, ISL) ,  WERGE Thomas (Copenhagen Univ. Hospital, Roskilde, DNK) ,  KIEMENEY Lambertus A (Radboud Univ. Nijmegen Medical Centre, Nijmegen, NLD) ,  PARVEZ Babar (Vanderbilt Univ. Medical Center, Tennessee, USA) ,  MUHAMMAD Raafia (Vanderbilt Univ. Medical Center, Tennessee, USA) ,  RODEN Dan M (Vanderbilt Univ. Medical Center, Tennessee, USA) ,  DARBAR Dawood (Vanderbilt Univ. Medical Center, Tennessee, USA)
Material： Nature Genetics  (Nat Genet)
Volume： 43  Issue： 4  Page： 316-320  Publication year： Apr. 2011 
JST Material Number： W0430A  ISSN： 1061-4036  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Thesaurus term： *gene ,  risk factor ,  Republic of Iceland ,  human ,  missense mutation ,  *sick sinus syndrome ,  Genotype ,  allele ,  heavy chain ,  myosin ,  Cardiac Myosins
Semi thesaurus term： *MYH6遺伝子 ,  Cardiac Muscle Myosins ,  *Sick Sinus Syndrome

JST classification (1)： Genetic variation  (EC01030Y)

Terms in the title (3)： 変異 ,  洞不全症候群 ,  リスク