Art

J-GLOBAL ID：201102227913446636   Reference number：11A1148448

Thymine DNA Glycosylase Is Essential for Active DNA Demethylation by Linked Deamination-Base Excision Repair

チミンDNAグリコシラーゼは連結された脱アミノ化-塩基除去修復によるアクティブなDNA脱メチル化に必須である

Author (27)： CORTELLINO Salvatore (Cancer Biology Program and Epigenetics and Progenitor Cells Keystone Program, Fox Chase Cancer Center, Philadelphia ...) ,  XU Jinfei (Cancer Biology Program and Epigenetics and Progenitor Cells Keystone Program, Fox Chase Cancer Center, Philadelphia ...) ,  SANNAI Mara (Cancer Biology Program and Epigenetics and Progenitor Cells Keystone Program, Fox Chase Cancer Center, Philadelphia ...) ,  MOORE Robert (Cancer Biology Program and Epigenetics and Progenitor Cells Keystone Program, Fox Chase Cancer Center, Philadelphia ...) ,  CARETTI Elena (Cancer Biology Program and Epigenetics and Progenitor Cells Keystone Program, Fox Chase Cancer Center, Philadelphia ...) ,  CIGLIANO Antonio (Cancer Biology Program and Epigenetics and Progenitor Cells Keystone Program, Fox Chase Cancer Center, Philadelphia ...) ,  LE COZ Madeleine (Cancer Biology Program and Epigenetics and Progenitor Cells Keystone Program, Fox Chase Cancer Center, Philadelphia ...) ,  DEVARAJAN Karthik (Dep. of Biostatistics, Fox Chase Cancer Center, Philadelphia, PA 19111, USA) ,  WESSELS Andy (Dep. of Cell Biology and Anatomy, Medical Univ. of South Carolina, Charleston, SC 29425, USA) ,  SOPRANO Dianne (Dep. of Biochemistry, Temple Univ. School of Medicine, Philadelphia, PA 19140, USA) ,  ABRAMOWITZ Lara K. (Dep. of Cell and Developmental Biology, Univ. of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA) ,  BARTOLOMEI Marisa S. (Dep. of Cell and Developmental Biology, Univ. of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA) ,  RAMBOW Florian (Inst. Curie, Centre de Rech., Developmental Genetics of Melanocytes, 91405 Orsay, FRA) ,  RAMBOW Florian (CNRS UMR3347 INSERM U1021, 91405 Orsay, FRA) ,  BASSI Maria Rosaria (Cancer Biology Program and Epigenetics and Progenitor Cells Keystone Program, Fox Chase Cancer Center, Philadelphia ...) ,  BRUNO Tiziana (Regina Elena Cancer Center, 00158 Rome, ITA) ,  FANCIULLI Maurizio (Regina Elena Cancer Center, 00158 Rome, ITA) ,  RENNER Catherine (Dep. of Pathology, Fox Chase Cancer Center, Philadelphia, PA 19111, USA) ,  KLEIN-SZANTO Andres J. (Dep. of Pathology, Fox Chase Cancer Center, Philadelphia, PA 19111, USA) ,  MATSUMOTO Yoshihiro (Dep. of Biological Sciences, East Stroudsburg Univ., East Stroudsburg, PA 18301, USA) ,  KOBI Dominique (Inst. de Genetique et de Biologie Moleculaire et Cellulaire, CNRS/INSERM/ULP, 67404 Illkirch, FRA) ,  DAVIDSON Irwin (Inst. de Genetique et de Biologie Moleculaire et Cellulaire, CNRS/INSERM/ULP, 67404 Illkirch, FRA) ,  ALBERTI Christophe (Inst. Curie, Centre de Rech., Developmental Genetics of Melanocytes, 91405 Orsay, FRA) ,  ALBERTI Christophe (CNRS UMR3347 INSERM U1021, 91405 Orsay, FRA) ,  LARUE Lionel (Inst. Curie, Centre de Rech., Developmental Genetics of Melanocytes, 91405 Orsay, FRA) ,  LARUE Lionel (CNRS UMR3347 INSERM U1021, 91405 Orsay, FRA) ,  BELLACOSA Alfonso (Cancer Biology Program and Epigenetics and Progenitor Cells Keystone Program, Fox Chase Cancer Center, Philadelphia ...)
Material： Cell (Cambridge, Mass.)  (Cell (Camb. Mass.))
Volume： 146  Issue： 1  Page： 67-79  Publication year： Jul. 08, 2011 
JST Material Number： A0707B  ISSN： 0092-8674  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Thesaurus term： *DNA glycosylase ,  *excision repair ,  *DNA lesion ,  promoter (genetics) ,  Proteins ,  nucleotide sequence ,  enhancer ,  Cytidine Deaminase ,  knockout mouse ,  Methylation ,  alicyclic compound ,  conjugated diene ,  terpenoid ,  unsaturated carboxylic acid ,  *Thymine DNA Glycosylase ,  *base excision repair ,  P300 ,  CpG Islands ,  DNA Methylation ,  activation-induced cytidine deaminase ,  laboratory animal ,  Mus musculus ,  vitamin A
Semi thesaurus term： AID

JST classification (2)： Molecular genetics in general  (EC02010J) ,  Enzyme in general  (EB09010D)

Substance index (1)： Tretinoin

Terms in the title (4)： チミンDNAグリコシラーゼ ,  脱アミノ化 ,  塩基除去修復 ,  DNA脱メチル化