Art

J-GLOBAL ID：201102231574736341   Reference number：11A1054839

TGF-β-activated kinase 1 mediates mechanical stress-induced IL-6 expression in osteoblasts

TGFβ-活性化キナーゼ1は骨芽細胞において機械的応力誘導のIL-6発現を媒介する

Author (11)： FUKUNO Naoto (Dep. of Biochemistry, Inst. of Dev., Aging and Cancer, Tohoku Univ., 4-1 Seiryo-machi, Aoba-ku, Sendai 980-8575, JPN) ,  FUKUNO Naoto (Divisions of Advanced Prosthetic Dentistry Graduate School of Dentistry, Tohoku Univ., 4-1 Seiryo-machi, Aoba-ku ...) ,  MATSUI Hiroyuki (Dep. of Biochemistry, Inst. of Dev., Aging and Cancer, Tohoku Univ., 4-1 Seiryo-machi, Aoba-ku, Sendai 980-8575, JPN) ,  MATSUI Hiroyuki (Divisions of Advanced Prosthetic Dentistry Graduate School of Dentistry, Tohoku Univ., 4-1 Seiryo-machi, Aoba-ku ...) ,  KANDA Yoshiaki (Dep. of Biochemistry, Inst. of Dev., Aging and Cancer, Tohoku Univ., 4-1 Seiryo-machi, Aoba-ku, Sendai 980-8575, JPN) ,  KANDA Yoshiaki (Divisions of Advanced Prosthetic Dentistry Graduate School of Dentistry, Tohoku Univ., 4-1 Seiryo-machi, Aoba-ku ...) ,  SUZUKI Osamu (Divisions of Craniofacial Function Engineering, Graduate School of Dentistry, Tohoku Univ., 4-1 Seiryo-machi ...) ,  MATSUMOTO Kunihiro (Dep. of Molecular Biology, Graduate School of Sci., Nagoya Univ., Chikusa-ku, Nagoya 464-8602, JPN) ,  SASAKI Keiichi (Divisions of Advanced Prosthetic Dentistry Graduate School of Dentistry, Tohoku Univ., 4-1 Seiryo-machi, Aoba-ku ...) ,  KOBAYASHI Takayasu (Dep. of Biochemistry, Inst. of Dev., Aging and Cancer, Tohoku Univ., 4-1 Seiryo-machi, Aoba-ku, Sendai 980-8575, JPN) ,  TAMURA Shinri (Dep. of Biochemistry, Inst. of Dev., Aging and Cancer, Tohoku Univ., 4-1 Seiryo-machi, Aoba-ku, Sendai 980-8575, JPN)
Material： Biochemical and Biophysical Research Communications  (BBRC)
Volume： 408  Issue： 2  Page： 202-207  Publication year： May. 06, 2011 
JST Material Number： B0118A  ISSN： 0006-291X  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Thesaurus term： *TGF beta ,  *phosphotransferase ,  *osteoblast ,  *stress(physiology) ,  *interleukin 6 ,  osteogenesis ,  drawing(extension) ,  calcium compound ,  metal ion ,  protein kinase ,  protein ,  MAP kinase kinase kinase ,  cultured cell ,  gene targetting ,  JNK MAP kinase ,  NF-kappaB ,  chelating reagent ,  cellular signal transduction ,  CaM kinase ,  mRNA ,  gene expression ,  protein synthesis ,  Western blotting ,  ELISA ,  primary culture
Semi thesaurus term： CaMKII ,  *IL6 ,  JNK ,  MAPKKK ,  MC3T3-E1 cell ,  P38 ,  TAK1 ,  Ca2+ ,  *kinase ,  chelating agent ,  signal transfer ,  knockdown ,  *Stress, Mechanical ,  Bone Remodeling ,  extension ,  Immunoblotting

JST classification (3)： Cytokines  (EB08090G) ,  Enzyme in general  (EB09010D) ,  Gene expression  (EC02040Q)

Terms in the title (7)： TGFβ ,  活性化 ,  キナーゼ ,  骨芽細胞 ,  機械的応力 ,  誘導 ,  発現