Art

J-GLOBAL ID：201102231731766411   Reference number：11A1473108

Exome Sequencing of Head and Neck Squamous Cell Carcinoma Reveals Inactivating Mutations in NOTCH1

頭頚部扁平上皮癌(HNSCC)のexomeシーケンシングはNOTCH1の不活性化変異を明らかにする

Author (35)： AGRAWAL Nishant (Johns Hopkins Univ. School of Medicine, MD, USA) ,  AGRAWAL Nishant (Johns Hopkins Kimmel Cancer Center, MD, USA) ,  FREDERICK Mitchell J. (Univ. Texas M.D. Anderson Cancer Center, TX, USA) ,  PICKERING Curtis R. (Univ. Texas M.D. Anderson Cancer Center, TX, USA) ,  BETTEGOWDA Chetan (Johns Hopkins Kimmel Cancer Center, MD, USA) ,  BETTEGOWDA Chetan (Johns Hopkins Univ. School of Medicine, MD, USA) ,  CHANG Kyle (Baylor Coll. Medicine, TX, USA) ,  LI Ryan J. (Johns Hopkins Univ. School of Medicine, MD, USA) ,  FAKHRY Carole (Johns Hopkins Univ. School of Medicine, MD, USA) ,  XIE Tong-Xin (Univ. Texas M.D. Anderson Cancer Center, TX, USA) ,  ZHANG Jiexin (Univ. Texas M.D. Anderson Cancer Center, TX, USA) ,  WANG Jing (Univ. Texas M.D. Anderson Cancer Center, TX, USA) ,  ZHANG Nianxiang (Univ. Texas M.D. Anderson Cancer Center, TX, USA) ,  EL-NAGGAR Adel K. (Univ. Texas M.D. Anderson Cancer Center, TX, USA) ,  JASSER Samar A. (Univ. Texas M.D. Anderson Cancer Center, TX, USA) ,  WEINSTEIN John N. (Univ. Texas M.D. Anderson Cancer Center, TX, USA) ,  TREVINO Lisa (Baylor Coll. Medicine, TX, USA) ,  DRUMMOND Jennifer A. (Baylor Coll. Medicine, TX, USA) ,  MUZNY Donna M. (Baylor Coll. Medicine, TX, USA) ,  WU Yuanqing (Baylor Coll. Medicine, TX, USA) ,  WOOD Laura D. (Johns Hopkins Univ. School of Medicine, MD, USA) ,  HRUBAN Ralph H. (Johns Hopkins Univ. School of Medicine, MD, USA) ,  WESTRA William H. (Johns Hopkins Univ. School of Medicine, MD, USA) ,  KOCH Wayne M. (Johns Hopkins Univ. School of Medicine, MD, USA) ,  CALIFANO Joseph A. (Johns Hopkins Univ. School of Medicine, MD, USA) ,  CALIFANO Joseph A. (Greater Baltimore Medical Center, MD, USA) ,  GIBBS Richard A. (Baylor Coll. Medicine, TX, USA) ,  GIBBS Richard A. (Greater Baltimore Medical Center, MD, USA) ,  SIDRANSKY David (Johns Hopkins Univ. School of Medicine, MD, USA) ,  VOGELSTEIN Bert (Johns Hopkins Kimmel Cancer Center, MD, USA) ,  VELCULESCU Victor E. (Johns Hopkins Kimmel Cancer Center, MD, USA) ,  PAPADOPOULOS Nickolas (Johns Hopkins Kimmel Cancer Center, MD, USA) ,  WHEELER David A. (Baylor Coll. Medicine, TX, USA) ,  KINZLER Kenneth W. (Johns Hopkins Kimmel Cancer Center, MD, USA) ,  MYERS Jeffrey N. (Univ. Texas M.D. Anderson Cancer Center, TX, USA)
Material： Science
Volume： 333  Issue： 6046  Page： 1154-1157  Publication year： Aug. 26, 2011 
JST Material Number： E0078A  ISSN： 0036-8075  CODEN： SCIEA  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Thesaurus term： *head and neck tumor ,  *squamous cell carcinoma ,  automatic analyser ,  *Notch receptor ,  mutation ,  copy number ,  smoking(tobacco) ,  *tumor suppressor gene ,  carcinogenesis ,  Papillomavirus
Semi thesaurus term： *Squamous cell carcinoma of the head and neck ,  next generation sequencer ,  *Notch1 ,  FBXW7遺伝子 ,  Papillomavirus, Human

JST classification (2)： Carcinogenic mechanisms and factors  (GE02020C) ,  Structure and chemistry of genes  (EC02020U)

Terms in the title (4)： 頭頚部扁平上皮癌 ,  Notch1 ,  不活性化 ,  変異