Art

J-GLOBAL ID：201102232946956480   Reference number：11A1359939

Structural Linkage between Ligand Discrimination and Receptor Activation by Type I Interferons

I型インターフェロンによるリガンド識別と受容体活性化の間の構造的連関性

Author (14)： THOMAS Christoph (Howard Hughes Medical Inst., Dep. of Molecular and Cellular Physiology and Dep. of Structural Biology, Stanford ...) ,  MORAGA Ignacio (Howard Hughes Medical Inst., Dep. of Molecular and Cellular Physiology and Dep. of Structural Biology, Stanford ...) ,  LEVIN Doron (Dep. of Biological Chemistry, Weizmann Inst. of Sci., Rehovot 76100, ISR) ,  KRUTZIK Peter O. (Dep. of Microbiology and Immunology, Baxter Lab in Stem Cell Biology, Stanford Univ. School of Medicine, Stanford ...) ,  PODOPLELOVA Yulia (Div. of Biophysics, Univ. of Osnabrueck, 49076 Osnabrueck, DEU) ,  TREJO Angelica (Dep. of Microbiology and Immunology, Baxter Lab in Stem Cell Biology, Stanford Univ. School of Medicine, Stanford ...) ,  LEE Choongho (Dep. of Medicine, Div. of Gastroenterology and Hepatology, Stanford Univ. School of Medicine, Stanford, CA 94305, USA) ,  YARDEN Ganit (Dep. of Biological Chemistry, Weizmann Inst. of Sci., Rehovot 76100, ISR) ,  VLECK Susan E. (Dep. of Medicine, Div. of Gastroenterology and Hepatology, Stanford Univ. School of Medicine, Stanford, CA 94305, USA) ,  GLENN Jeffrey S. (Dep. of Medicine, Div. of Gastroenterology and Hepatology, Stanford Univ. School of Medicine, Stanford, CA 94305, USA) ,  NOLAN Garry P. (Dep. of Microbiology and Immunology, Baxter Lab in Stem Cell Biology, Stanford Univ. School of Medicine, Stanford ...) ,  PIEHLER Jacob (Div. of Biophysics, Univ. of Osnabrueck, 49076 Osnabrueck, DEU) ,  SCHREIBER Gideon (Dep. of Biological Chemistry, Weizmann Inst. of Sci., Rehovot 76100, ISR) ,  GARCIA K. Christopher (Howard Hughes Medical Inst., Dep. of Molecular and Cellular Physiology and Dep. of Structural Biology, Stanford ...)
Material： Cell (Cambridge, Mass.)  (Cell (Camb. Mass.))
Volume： 146  Issue： 4  Page： 621-632  Publication year： Aug. 19, 2011 
JST Material Number： A0707B  ISSN： 0092-8674  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Thesaurus term： *interferon ,  human(primates) ,  interferon alpha ,  *cytokine receptor ,  amino acid sequence ,  steric conformation ,  binding site ,  antiviral action ,  protein complex ,  dissociation constant ,  STAT transcription factor ,  inhibition of multiplication
Semi thesaurus term： *type I interferon ,  interferon omega ,  *IFN alpha receptor ,  IFNAR1 ,  IFNAR2

JST classification (2)： Receptors on cell membrane  (EF04030C) ,  Cytokines  (EB08090G)

Terms in the title (6)： I型インターフェロン ,  リガンド ,  識別 ,  受容体 ,  活性化 ,  連関