Art
J-GLOBAL ID：201102234384015850   Reference number：11A1316365

関節リウマチ治療におけるメトトレキサート療法

Author (2)：
YAMAMOTO KAZUHIKO

About YAMAMOTO KAZUHIKO

(東大 大学院医学系研究科 内科学専攻 アレルギー・リウマチ学)

About 東大 大学院医学系研究科 内科学専攻 アレルギー・リウマチ学

, 
OGAWA YOSHIKO

About OGAWA YOSHIKO

(ファイザー)

About ファイザー


Material：
新薬と臨床  (Journal of New Remedies & Clinics)

About 新薬と臨床


Volume： 60  Issue： 8  Page： 1523-1540  Publication year： Aug. 10, 2011 
JST Material Number： G0596A  ISSN： 0559-8672  CODEN： SHRIA  Document type： Article
Article type： 文献レビュー  Country of issue： Japan (JPN)  Language： JAPANESE (JA)
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*antirheumatic drug

About antirheumatic drug

,...
Semi thesaurus term：
Thesaurus term/Semi thesaurus term
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rheumatoid arthritis

About rheumatoid arthritis

,...
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JST classification (3)：
JST classification
Category name(code) classified by JST.
Clinical application of anti-inflammatory drugs 
(GW15020E)

About Clinical application of anti-inflammatory drugs

,  Clinical biopharmacy 
(GY01022L)

About Clinical biopharmacy

,  Interactions of drugs 
(GV01070X)

About Interactions of drugs

Substance index (1)：
Substance index
Chemical Substance indexed to the Article.
Methotrexate

About Methotrexate

Reference (60)：
  • 1) Walling J. From methotrexate to pemetrexed and beyond. A review of the pharmacodynamic and clinical properties of antifolates. Invest New Drugs. 2006 ; 24 : 37-77.
  • 2) Ranganathan P. An update on methotrexate pharmacogenetics in rheumatoid arthritis. Pharmacogenomics. 2008 ; 9 : 439-451.
  • 3) Sperling RI, et al. Inhibition of leukotriene B4 synthesis in neutrophils from patients with rheumatoid arthritis by a single oral dose of methotrexate. Arthritis Rheum. 1990 : 33 : 1149-1155.
  • 4) Nesher G, et al. The in vitro effects of methotrexate on peripheral blood mononuclear cells. Modulation by methyl donors and spermidine. Arthritis Rheum. 1990 ; 33 : 954-959.
  • 5) Cronstein BN, et al. The antiinflammatory mechanism of methotrexate. Increased adenosine release at inflamed sites diminishes leukocyte accumulation in an in vivo model of inflammation. J Clin Invest. 1993 ; 92 : 2675-2682.
ｍore...
Terms in the title (4)：
Terms in the title
Keywords automatically extracted from the title.
関節リウマチ

About 関節リウマチ

, 
治療

About 治療

, 
メトトレキサート

About メトトレキサート

, 
療法

About 療法


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