Art

J-GLOBAL ID：201102235491140418   Reference number：11A0999733

Hydroxylation of 5-Methylcytosine by TET1 Promotes Active DNA Demethylation in the Adult Brain

TET1による5-メチルシトシンのヒドロキシ化は成体脳における活性DNA脱メチル化を促進する

Author (12)： GUO Junjie U. (Inst. for Cell Engineering, Johns Hopkins Univ. School of Medicine, Baltimore, MD 21205, USA) ,  GUO Junjie U. (The Solomon H. Snyder Dep. of Neuroscience, Johns Hopkins Univ. School of Medicine, Baltimore, MD 21205, USA) ,  SU Yijing (Inst. for Cell Engineering, Johns Hopkins Univ. School of Medicine, Baltimore, MD 21205, USA) ,  SU Yijing (Dep. of Neurology, Johns Hopkins Univ. School of Medicine, Baltimore, MD 21205, USA) ,  ZHONG Chun (Inst. for Cell Engineering, Johns Hopkins Univ. School of Medicine, Baltimore, MD 21205, USA) ,  ZHONG Chun (Dep. of Neurology, Johns Hopkins Univ. School of Medicine, Baltimore, MD 21205, USA) ,  MING Guo-li (Inst. for Cell Engineering, Johns Hopkins Univ. School of Medicine, Baltimore, MD 21205, USA) ,  MING Guo-li (The Solomon H. Snyder Dep. of Neuroscience, Johns Hopkins Univ. School of Medicine, Baltimore, MD 21205, USA) ,  MING Guo-li (Dep. of Neurology, Johns Hopkins Univ. School of Medicine, Baltimore, MD 21205, USA) ,  SONG Hongjun (Inst. for Cell Engineering, Johns Hopkins Univ. School of Medicine, Baltimore, MD 21205, USA) ,  SONG Hongjun (The Solomon H. Snyder Dep. of Neuroscience, Johns Hopkins Univ. School of Medicine, Baltimore, MD 21205, USA) ,  SONG Hongjun (Dep. of Neurology, Johns Hopkins Univ. School of Medicine, Baltimore, MD 21205, USA)
Material： Cell (Cambridge, Mass.)  (Cell (Camb. Mass.))
Volume： 145  Issue： 3  Page： 423-434  Publication year： Apr. 29, 2011 
JST Material Number： A0707B  ISSN： 0092-8674  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Thesaurus term： mouse(animal) ,  dentate gyrus ,  demethylation ,  *excision repair ,  *cytidine deaminase ,  *DNA binding protein ,  DNA methyltransferase ,  gene expression ,  deamination ,  neurophysiology ,  *hydroxylation
Semi thesaurus term： *hydroxylation ,  APOBEC ,  DNA-Cytosine Methylases ,  DNA demethylation ,  *TET1蛋白質 ,  Activation-Induced Cytidine Deaminase

JST classification (2)： Molecular genetics in general  (EC02010J) ,  Basic neurology  (GN01020W)

Substance index (1)： 5-Methylcytosine

Terms in the title (8)： TET1 ,  5-メチルシトシン ,  ヒドロキシ化 ,  成体 ,  脳 ,  活性 ,  DNA脱メチル化 ,  促進