Art

J-GLOBAL ID：201102237150850894   Reference number：11A0506078

Interaction defect of the medium isoform of PTS1-receptor Pex5p with PTS2-receptor Pex7p abrogates the PTS2 protein import into peroxisomes in mammals

PTS1受容体Pex5pとPTS2受容体Pex7pの中間イソ型の相互作用欠損は哺乳類におけるペルオキシソームへのPTS2蛋白質輸入が消失する

Author (5)： HONSHO Masanori (Kyushu Univ., Fukuoka) ,  HASHIGUCHI Yasuko (Kyushu Univ., Fukuoka) ,  GHAEDI Kamran (Kyushu Univ., Fukuoka) ,  FUJIKI Yukio (Kyushu Univ., Fukuoka) ,  FUJIKI Yukio (JST-CREST, Tokyo, JPN)
Material： Journal of Biochemistry  (JB)
Volume： 149  Issue： 2  Page： 203-210  Publication year： Feb. 2011 
JST Material Number： W1920A  ISSN： 0021-924X  CODEN： JOBIAO  Document type： Article
Article type： 原著論文  Country of issue： United Kingdom (GBR)  Language： ENGLISH (EN)

Thesaurus term： *membrane protein ,...
Semi thesaurus term： CHO-K1 cell ,...

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JST classification (2)： Cell physiology in general  (EF02010S) ,  Structure and chemistry of genes  (EC02020U)

Reference (33)：

• FUJIKI, Y. Lessons from peroxisome-deficient Chinese hamster ovary (CHO) cell mutants. Biochim. Biophys. Acta-Mol. Cell Res. 2006, 1763, 1374-1381
• LAZAROW, P. B. Biogenesis of peroxisomes. Annu. Rev. Cell Biol. 1985, 1, 489-530
• SUBRAMANI, S. Import of peroxisomal matrix and membrane proteins. Annu. Rev. Biochem. 2000, 69, 399-418
• OTERA, H. Peroxisome targeting signal type 1 (PTS1) receptor is involved in import of both PTS1 and PTS2 : studies with PEX5-defective CHO cell mutants. Mol. Cell. Biol. 1998, 18, 388-399
• OTERA, H. The mammalian peroxin Pex5pL, the longer isoform of the mobile PTS1-transporter, translocates Pex7p-PTS2 protein complex into peroxisomes via its initial docking site, Pex14p. J. Biol. Chem. 2000, 275, 21703-21714

Terms in the title (11)： PTS1受容体 ,  Pex5p ,  PTS2受容体 ,  Pex7p ,  イソ型 ,  相互作用 ,  欠損 ,  哺乳類 ,  ペルオキシソーム ,  PTS2 ,  蛋白質輸入