Art

J-GLOBAL ID：201102238768841515   Reference number：11A1659976

Discovery and structural characterization of a small molecule 14-3-3 protein-protein interaction inhibitor

低分子14-3-3蛋白質-蛋白質相互作用抑制因子の発見と構造的特徴づけ

Author (17)： ZHAO Jing (Emory Univ. School of Medicine, GA) ,  ZHAO Jing (Fourth Military Medical Univ., Xi’an, CHN) ,  DU Yuhong (Emory Univ. School of Medicine, GA) ,  HORTON John R. (Emory Univ. School of Medicine, GA) ,  UPADHYAY Anup K. (Emory Univ. School of Medicine, GA) ,  LOU Bin (Emory Univ. School of Medicine, GA) ,  BAI Yan (Emory Univ. School of Medicine, GA) ,  ZHANG Xing (Emory Univ. School of Medicine, GA) ,  DU Lupei (Georgia State Univ., GA) ,  LI Minyong (Georgia State Univ., GA) ,  WANG Binghe (Georgia State Univ., GA) ,  ZHANG Lixin (Emory Univ. School of Medicine, GA) ,  ZHANG Lixin (Inst. Microbiology, Chinese Acad. Sci., Beijing, CHN) ,  BARBIERI Joseph T. (Medical Coll. Wisconsin, WI) ,  KHURI Fadlo R. (Emory Univ. School of Medicine, GA) ,  CHENG Xiaodong (Emory Univ. School of Medicine, GA) ,  FU Haian (Emory Univ. School of Medicine, GA)
Material： Proceedings of the National Academy of Sciences of the United States of America  (PNAS)
Volume： 108  Issue： 39  Page： 16212-16216  Publication year： Sep. 27, 2011 
JST Material Number： D0387A  ISSN： 0027-8424  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Thesaurus term： *adaptor protein ,  ADP ribosyltransferase ,  enzyme ,  crystal structure analysis ,  intermolecular interaction ,  ELISA ,  crystal structure ,  covalent bond ,  Western blotting ,  MALDI-TOF MS ,  TOF ,  14-3-3 zeta ,  *14-3-3 Proteins ,  Extracellular Enzymes ,  Benzoates ,  bioassay

JST classification (1)： Biological function  (EB03040U)

Substance index (1)： FOBISIN101

Terms in the title (5)： 低分子 ,  14-3-3蛋白質 ,  蛋白質相互作用 ,  抑制因子 ,  発見