Art

J-GLOBAL ID：201102239977372812   Reference number：11A1263111

Increased Wingless (Wnt) signaling in pituitary progenitor/stem cells gives rise to pituitary tumors in mice and humans

マウスとヒトでは下垂体前駆細胞/幹細胞のWingless(Wnt)シグナル伝達が増加すると下垂体腫瘍が起る

Author (13)： GASTON-MASSUET Carles (Univ. Coll. London Inst. Child Health, London, GBR) ,  ANDONIADOU Cynthia Lilian (Univ. Coll. London Inst. Child Health, London, GBR) ,  SIGNORE Massimo (Univ. Coll. London Inst. Child Health, London, GBR) ,  JAYAKODY Sujatha A. (Univ. Coll. London Inst. Child Health, London, GBR) ,  CHAROLIDI Nicoletta (Univ. Coll. London Inst. Child Health, London, GBR) ,  KYEYUNE Roger (Great Ormond Street Hospital for Children, London, GBR) ,  VERNAY Bertrand (Univ. Coll. London Inst. Child Health, London, GBR) ,  JACQUES Thomas S. (Univ. Coll. London Inst. Child Health, London, GBR) ,  JACQUES Thomas S. (Great Ormond Street Hospital for Children, London, GBR) ,  TAKETO Makoto Mark (Kyoto Univ., Kyoto, JPN) ,  LE TISSIER Paul (National Inst. Medical Res., London, GBR) ,  DATTANI Mehul T. (Univ. Coll. London Inst. Child Health, London, GBR) ,  MARTINEZ-BARBERA Juan Pedro (Univ. Coll. London Inst. Child Health, London, GBR)
Material： Proceedings of the National Academy of Sciences of the United States of America  (PNAS)
Volume： 108  Issue： 28  Page： 11482-11487  Publication year： Jul. 12, 2011 
JST Material Number： D0387A  ISSN： 0027-8424  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Thesaurus term： catenin ,  transcription factor ,  *pituitary gland ,  hyperplasia ,  ES cell ,  pituitary disease ,  head and neck tumor ,  muscle tissue tumor ,  connective tissue tumor ,  bone tumor ,  soft tissue tumor ,  benign tumor ,  *tumorigenesis ,  beta Catenin ,  *Signal Transduction ,  *Wnt Signaling Pathway ,  Proteins
Semi thesaurus term： *cellular signal transduction ,  *tumorigenesis ,  Rathke's pouch ,  *Wnt signaling ,  Hyperplasia ,  *Tumorigenesis ,  Epithelioma ,  Craniopharyngioma

JST classification (2)： Cell physiology in general  (EF02010S) ,  Carcinogenic mechanisms and factors  (GE02020C)

Terms in the title (9)： マウス ,  ヒト ,  下垂体 ,  前駆細胞 ,  幹細胞 ,  Wingless ,  Wnt ,  シグナル伝達 ,  下垂体腫瘍