Art

J-GLOBAL ID：201102240537921430   Reference number：11A0556679

An Interlaboratory Collaborative Study on a Cell Transformation Assay Using Bhas 42 Cells

Bhas42細胞を用いた細胞形質転換アッセイの研究室間の共同研究

Author (18)： TANAKA Noriho (Food and Drug Safety Center) ,  SASAKI Kiyoshi (Food and Drug Safety Center) ,  HAYASHI Kumiko (Food and Drug Safety Center) ,  SAKAI Ayako (Food and Drug Safety Center) ,  ASADA Shin (Food and Drug Safety Center) ,  MURAMATSU Dai (Food and Drug Safety Center) ,  KURODA Sachiko (Food and Drug Safety Center) ,  MIZUHASHI Fukutaro (Biosafety Res. Center) ,  NAGAI Miho (Biosafety Res. Center) ,  SUZUKI Hiroshi (Ina Res. Inc) ,  IMAMURA Tadashi (Ina Res. Inc) ,  ASAKURA Masumi (Japan Bioassay Res. Center) ,  SATOH Hidetaka (Japan Food Res. Lab.) ,  SAKAMOTO Akiko (Japan Food Res. Lab.) ,  NAKAO Ryosuke (Japan Food Res. Lab.) ,  HIROSE Hideki (Mitsubishi Chemical Safety Inst. Ltd.) ,  ISHII Nana (Mitsubishi Chemical Safety Inst. Ltd.) ,  UMEDA Makoto (Food and Drug Safety Center)
Material： Alternatives to Animal Testing and Experimentation  (AATEX)
Volume： 14  Issue： 1  Page： 831-848  Publication year： Mar. 31, 2009 
JST Material Number： L5507A  ISSN： 1344-0411  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *cultured cell ,...

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JST classification (1)： Carcinogenic mechanisms and factors  (GE02020C)

Reference (37)：

• ASADA, S. Detection of initiating as well as promoting activity of chemicals by a novel cell transformation assay using v-Ha-ras-transfected BALB/c 3T3 cells (Bhas 42 cells). Mutat Res. 2005, 588, 7-21
• ASHBY, J. Chemical structure, Salmonella mutagenicity and extent of carcinogenicity as indicators of genotoxic carcinogenesis among 222 chemicals tested in rodents by the U.S. NCI/NTP. Mutat Res. 1988, 204, 17-115
• BARRETT, J. C. Use of cell transformation systems for carcinogenicity testing and mechanistic studies of carcinogenesis. Pharmacol Rev. 1984, 36, 53S-70S
• BEEKMAN, J. M. Gene expression analysis of the hepatotoxicant methapyrilene in primary rat hepatocytes : an interlaboratory study. Environ Health Perspect. 2006, 114, 92-99
• BERENBLUM, I. The cocarcinogenic action of croton resin. Cancer Res. 1941, 1, 44-48

Terms in the title (5)： Bhas42細胞 ,  細胞形質転換 ,  アッセイ ,  研究 ,  共同