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J-GLOBAL ID：201102247306362866   Reference number：11A1890352

脳の機能と統合失調症-新たな診断と治療への展望-I 統合失調症のゲノムワイド関連解析(GWAS)

Author (1)： YAMADA KAZUO (理研 脳科学総合研究セ)
Material： 精神科治療学  (Japanese Journal of Psychiatric Treatment)
Volume： 26  Issue： 11  Page： 1379-1385  Publication year： Nov. 19, 2011 
JST Material Number： X0617A  ISSN： 0912-1862  Document type： Article
Article type： 文献レビュー  Country of issue： Japan (JPN)  Language： JAPANESE (JA)

Thesaurus term： *schizophrenia ,...
Semi thesaurus term： Genome-Wide Association Study ,...

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JST classification (1)： Mental disorders  (GR03000A)

Reference (14)：

• 1) Glessner, J.T., Wang, K., Cai, G. et al. : Autism genome謡ide copy number variation reveals ubiquitin and neuronal genes. Nature, 459 ; 569- 573, 2009.
• 2) Ikeda, M., Aleksic, B., Kinoshita, Y. et al. : Ge- nome謡ide association study of schizophrenia in a Japanese population. Biol. Psychiatry, 69 ; 472-478, 2011.
• 3) The International Schizophrenia Consortium : Rare chromosomal deletions and duplications increase risk of schizophrenia. Nature, 455 ;237-241, 2008.
• 4) Kirov, G., Grozeva, D., Norton, N. et al.: Support for the involvement of large copy number vari- ants in the pathogenesis of schizophrenia. Hum. Mol. Genet., 18 ;1497-1503, 2009.
• 5) Marshall, C.R., Noor, A., Vincent, J.B. et al. : Structural variation of chromosomes in autism spectrum disorder. Am. J. Hum. Genet., 82 ; 477-488, 2008.

Terms in the title (7)： 脳 ,  統合失調症 ,  診断 ,  治療 ,  展望 ,  ゲノムワイド関連解析 ,  GWAS