Art

J-GLOBAL ID：201102247824534123   Reference number：11A1668199

Short, Enantioselective Total Syntheses of (-)-8-Demethoxyrunanine and (-)-Cepharatines A, C, and D

(-)-8-デメトキシルナニン及び(-)-セファラチンA,C,ならびにDの短経路で,エナンチオ選択的な全合成

Author (3)： CHUANG Kangway V. (California Inst. of Technol., CA, USA) ,  NAVARRO Raul (California Inst. of Technol., CA, USA) ,  REISMAN Sarah E. (California Inst. of Technol., CA, USA)
Material： Angewandte Chemie. International Edition  (Angewandte Chemie. International Edition in English)
Volume： 50  Issue： 40  Page： 9447-9451  Publication year： 2011 
JST Material Number： H0127B  ISSN： 1433-7851  CODEN： ACIEAY  Document type： Article
Article type： 短報  Country of issue： Germany, Federal Republic of (DEU)  Language： ENGLISH (EN)

Thesaurus term： *alkaloid ,  total synthesis ,  asymmetric synthesis ,  *Grignard reaction ,  *substitution reaction
Semi thesaurus term： (-)-8-デメトキシルナニン ,  (-)-セファラチンA ,  (-)-セファラチンC ,  (-)-セファラチンD

JST classification (2)： Alkaloids  (CF10030D) ,  Plant biochemistry  (EH01050J)

Substance index (14)： 2-Bromo-4-methoxyphenol ,  3-Bromo-4-(tert-butylsulfinylimino)-2,5-cyclohexadiene-1-one dimethyl acetal ,  (4R)-3-Bromo-4α-[tert-butylsulfinyl(methyl)amino]-4-(3,4-dimethoxyphenethyl)-2,5-cyclohexadiene-1-one dimethyl acetal ,  (4R)-3-Bromo-4α-[tert-butylsulfinyl(methyl)amino]-4-[3-[2-(trimethylsilyl)ethyl]-4-methoxyphenethyl]-2,5-cyclohexadiene-1-one dimethyl acetal ,  (4R)-3-(2-Ethoxyethenyl)-4α-[tert-butylsulfinyl(methyl)amino]-4-(3,4-dimethoxyphenethyl)-2,5-cyclohexadiene-1-one dimethyl acetal ,  (4R)-3-(2-Ethoxyethenyl)-4α-[tert-butylsulfinyl(methyl)amino]-4-[3-[2-(trimethylsilyl)ethyl]-4-methoxyphenethyl]-2,5-cyclohexadiene-1-one dimethyl acetal ,  (7aR)-1-Methyl-7aα-(3,4-dimethoxyphenethyl)-2,3,5,7a-tetrahydro-1H-indole-5-one ,  (7aR)-1-Methyl-7aα-[3-[2-(trimethylsilyl)ethyl]-4-methoxyphenethyl]-2,3,5,7a-tetrahydro-1H-indole-5-one ,  (4aS)-6,7-Dimethoxy-11-methyl-10aα,4aα-(epiminoethano)-3,4,4a,9,10,10a-hexahydrophenanthrene-3-one ,  (4aS)-5-Hydroxy-6-methoxy-8-bromo-11-methyl-10aα,4aα-(epiminoethano)-3,4,4a,9,10,10a-hexahydrophenanthrene-3-one ,  Cepharatine D ,  Cepharatine A ,  Cepharatine C ,  8-Demethoxyrunanine

Terms in the title (2)： 経路 ,  全合成