Art

J-GLOBAL ID：201102249438657426   Reference number：11A1040261

Methylmercury inhibits electron transport chain activity and induces cytochrome c release in cerebellum mitochondria

小脳ミトコンドリアにおいてメチル水銀は電子伝達系活動を阻害しチトクロームc遊離を誘発する

Author (4)： MORI Nobuko (Dep. of Biomedical Lab. Sciences, Fac. of Life Sciences, Kumamoto Univ.) ,  YASUTAKE Akira (National Inst. for Minamata Disease) ,  MARUMOTO Masumi (National Inst. for Minamata Disease) ,  HIRAYAMA Kimiko (Dep. of Biomedical Lab. Sciences, Fac. of Life Sciences, Kumamoto Univ.)
Material： Journal of Toxicological Sciences  (J Toxicol Sci)
Volume： 36  Issue： 3  Page： 253-259 (J-STAGE)  Publication year： 2011 
JST Material Number： Z0265B  ISSN： 0388-1350  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： rat ,...
Semi thesaurus term： Caspase 3 ,...

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JST classification (2)： Basic neurology  (GN01020W) ,  Toxicity of metals and metal compounds  (GZ02022V)

Substance index (1)： Methylmercury

Reference (42)：

• ALI, S. F. Reactive oxygen species formation as a biomarker of methylmercury and trimethyltin neurotoxicity. Neurotoxicology. 1992, 13, 637-648
• BARNHAM, K. J. Neurodegenerative diseases and oxidative stress. Nat. Rev. Drug Discov. 2004, 3, 205-214
• BONDY, S. C. Prevention of chemically induced synaptosomal changes. J. Neurosci. Res. 1990, 25, 229-235
• CAI, J. Mitochondrial control of apoptosis : the role of cytochrome c. Biochim. Biophys. Acta. 1998, 1366, 139-149
• CAPALDI, R. A. Structural features of the mitochondrial electron-transfer chain. Curr. Opin. Struct. Biol. 1991, 1, 562-568

Terms in the title (7)： 脳ミトコンドリア ,  メチル水銀 ,  電子伝達系 ,  活動 ,  阻害 ,  チトクロームC ,  誘発