Art

J-GLOBAL ID：201102252754510284   Reference number：11A1527650

Preparation of spray-dried microparticles using Gelucire 44/14 and porous calcium silicate or spherical microcrystalline cellulose to enhance transport of water-insoluble pranlukast hemihydrate across Caco-2 monolayers

Caco-2単一層を通る水不溶性プランルカスト半水和物の輸送を向上させるための,Gelcire44/14,および多孔性ケイ酸カルシウムまたは球状微結晶セルロースを用いた噴霧乾燥微粒子の調製

Author (8)： OZEKI Tetsuya (Graduate School of Pharmaceutical Sciences, Nagoya City Univ., 3-1 Tanabe-dori, Mizuho-ku, Nagoya, Aichi 467-8603, JPN) ,  TAKASHIMA Yuuki (School of Pharmacy, Tokyo Univ. of Pharmacy and Life Sciences, 1432-1 Horinouchi, Hachioji, Tokyo 192-0392, JPN) ,  NAKANO Tatsu (School of Pharmacy, Tokyo Univ. of Pharmacy and Life Sciences, 1432-1 Horinouchi, Hachioji, Tokyo 192-0392, JPN) ,  YUASA Hiroshi (School of Clinical Pharmacy, Coll. of Pharmaceutical Sciences, Matsuyama Univ., 4-1 Bunkyo-Cho, Matsuyama, Ehime ...) ,  KATAOKA Makoto (Fac. of Pharmaceutical Sciences, Setsunan Univ., 45-1 Nagaotoge-cho, Hirakata, Osaka 573-0101, JPN) ,  YAMASHITA Shinji (Fac. of Pharmaceutical Sciences, Setsunan Univ., 45-1 Nagaotoge-cho, Hirakata, Osaka 573-0101, JPN) ,  TATSUMI Taiga (Graduate School of Pharmaceutical Sciences, Nagoya City Univ., 3-1 Tanabe-dori, Mizuho-ku, Nagoya, Aichi 467-8603, JPN) ,  OKADA Hiroaki (School of Pharmacy, Tokyo Univ. of Pharmacy and Life Sciences, 1432-1 Horinouchi, Hachioji, Tokyo 192-0392, JPN)
Material： Advanced Powder Technology  (Adv Powder Technol)
Volume： 22  Issue： 5  Page： 623-628  Publication year： Sep. 2011 
JST Material Number： W0255A  ISSN： 0921-8831  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Thesaurus term： *Caco2 cell ,...
Semi thesaurus term： Tween80 ,...

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JST classification (2)： Solid preparations  (GY02030V) ,  Powder technology  (XD03010M)

Substance index (1)： Onon

Reference (45)：

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• SEKIGUCHI, K. Studies on absorption of eutectic mixture. I. A comparison of the behavior of eutectic mixture of sulfathiazole and that of ordinary sulfathiazole in man. Chem. Pharm. Bull. 1961, 9, 866-872
• CHIOU, W. L. Pharmaceutical applications of solid dispersion systems. J. Pharm. Sci. 1971, 60, 1281-1302

Terms in the title (13)： Caco-2 ,  単一層 ,  水不溶 ,  プランルカスト ,  水和物 ,  輸送 ,  多孔性 ,  ケイ酸カルシウム ,  球状 ,  微結晶セルロース ,  噴霧乾燥 ,  微粒子 ,  調製