Art

J-GLOBAL ID：201102252780962789   Reference number：11A1157872

Oncogene-induced Nrf2 transcription promotes ROS detoxification and tumorigenesis

がん遺伝子に誘導されたNrf2の転写はROSの無毒化と腫瘍発生を促進する

Author (20)： DENICOLA Gina M. (Cancer Res. UK Cambridge Inst., Cambridge, GBR) ,  KARRETH Florian A. (Cancer Res. UK Cambridge Inst., Cambridge, GBR) ,  HUMPTON Timothy J. (Cancer Res. UK Cambridge Inst., Cambridge, GBR) ,  GOPINATHAN Aarthi (Cancer Res. UK Cambridge Inst., Cambridge, GBR) ,  FRESE Kristopher (Cancer Res. UK Cambridge Inst., Cambridge, GBR) ,  TUVESON David A. (Cancer Res. UK Cambridge Inst., Cambridge, GBR) ,  DENICOLA Gina M. (Univ. Pennsylvania, Pennsylvania, USA) ,  GOPINATHAN Aarthi (Univ. Pennsylvania, Pennsylvania, USA) ,  KARRETH Florian A. (Univ. Vienna, Vienna, AUT) ,  WEI Cong (Univ. Pennsylvania, Pennsylvania, USA) ,  MANGAL Dipti (Univ. Pennsylvania, Pennsylvania, USA) ,  YU Kenneth H. (Univ. Pennsylvania, Pennsylvania, USA) ,  BLAIR Ian A. (Univ. Pennsylvania, Pennsylvania, USA) ,  YEO Charles J. (Jefferson Medical Coll., Pennsylvania, USA) ,  CALHOUN Eric S. (Alma Coll., Michigan, USA) ,  SCRIMIERI Francesca (Johns Hopkins Medical Institutions, Maryland, USA) ,  HRUBAN Ralph H. (Johns Hopkins Medical Institutions, Maryland, USA) ,  IACOBUZIO-DONAHUE Christine (Johns Hopkins Medical Institutions, Maryland, USA) ,  KERN Scott E. (Johns Hopkins Medical Institutions, Maryland, USA) ,  WINTER Jordan M. (Johns Hopkins Medical Institutions, Maryland, USA)
Material： Nature (London)  (Nature (Lond))
Volume： 475  Issue： 7354  Page： 106-109  Publication year： Jul. 07, 2011 
JST Material Number： D0193B  ISSN： 0028-0836  Document type： Article
Article type： 原著論文  Country of issue： United Kingdom (GBR)  Language： ENGLISH (EN)

Thesaurus term： *oncogene ,  DNA binding protein ,  *transcription factor ,  active oxygen ,  detoxication ,  Carcinogenesis ,  transcription (genetics) ,  gene expression ,  antioxidation ,  MAP kinase kinase kinase ,  oncoprotein ,  Ras protein ,  Mus musculus ,  allele ,  K-ras ,  transcription control ,  Gene Expression Regulation ,  Proto-Oncogene Proteins B-raf ,  *NF-E2-Related Factor 2 ,  molecular genetic phenomenon ,  Myomorpha ,  Heredity
Semi thesaurus term： genetic regulation ,  B-Raf ,  Myc ,  *NRF2

JST classification (2)： Gene expression  (EC02040Q) ,  Carcinogenic mechanisms and factors  (GE02020C)

Terms in the title (8)： がん遺伝子 ,  誘導 ,  NRF2 ,  転写 ,  ROS ,  無毒化 ,  腫瘍発生 ,  促進