Art

J-GLOBAL ID：201102255010020032   Reference number：11A1691348

Engineering the substrate specificity of Alcaligenes d-aminoacylase useful for the production of d-amino acids by optical resolution

光学分割によるD-アミノ酸の産生に有用なAlcaligenesのD-アミノアシラーゼの基質特異性のエンジニアリング

Author (7)： YANO Shigekazu (Dep. of Biotechnology, Coll. of Life Sciences, Ritsumeikan Univ., Kusatsu, 1-1-1 Noji-higashi, Kusatsu, Shiga ...) ,  HARUTA Hiroyuki (Dep. of Biotechnology, Coll. of Life Sciences, Ritsumeikan Univ., Kusatsu, 1-1-1 Noji-higashi, Kusatsu, Shiga ...) ,  IKEDA Takuya (Dep. of Biotechnology, Coll. of Life Sciences, Ritsumeikan Univ., Kusatsu, 1-1-1 Noji-higashi, Kusatsu, Shiga ...) ,  KIKUCHI Takeshi (Dep. of Bioinformatics, Coll. of Life Sciences, Ritsumeikan Univ., Kusatsu, Shiga, 525-8577, JPN) ,  MURAKAMI Masahiro (Dep. of Biotechnology, Coll. of Life Sciences, Ritsumeikan Univ., Kusatsu, 1-1-1 Noji-higashi, Kusatsu, Shiga ...) ,  MORIGUCHI Mitsuaki (Dep. of Food and Bioscience, Beppu Univ., 82 Kitaishigaki Beppu, Oita 874-8501, JPN) ,  WAKAYAMA Mamoru (Dep. of Biotechnology, Coll. of Life Sciences, Ritsumeikan Univ., Kusatsu, 1-1-1 Noji-higashi, Kusatsu, Shiga ...)
Material： Journal of Chromatography B  (Journal of Chromatography B. Analytical Technologies in the Biomedical and Life Sciences)
Volume： 879  Issue： 29  Page： 3247-3252  Publication year： Nov. 01, 2011 
JST Material Number： W0571A  ISSN： 1570-0232  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Thesaurus term： *optical resolution ,  *amino acid ,  *aminoacylase ,  *substrate specificity ,  *Bacillus ,  mixture ,  primary structure ,  amino acid residue ,  mutant ,  intermolecular interaction ,  efficiency ,  pH dependence ,  temperature dependence ,  block(object) ,  circuit module ,  enzymatic synthesis ,  circular dichroism spectrum ,  tertiary structure
Semi thesaurus term： *Alcaligenes xylosoxidans ,  *D-amino acid ,  building block ,  racemic mixture ,  catalytic efficiency

JST classification (2)： Physical analysis of organic compounds  (CC03034A) ,  Proteins and peptides in general  (EB03010N)

Terms in the title (6)： 光学分割 ,  D-アミノ酸 ,  Alcaligenes ,  アミノアシラーゼ ,  基質特異性 ,  エンジニアリング