Art

J-GLOBAL ID：201102255979109413   Reference number：11A1044221

S100A8/A9 induces autophagy and apoptosis via ROS-mediated cross-talk between mitochondria and lysosomes that involves BNIP3

S100A8/A9はBNIP3に関与するミトコンドリアとリソソームのROS仲介クロストークによりオートファジーおよびアポトーシスを誘導する

Author (10)： Saeid Ghavami (Dep. of Biochemistry and Medical Genetics, Manitoba Inst. of Cell Biology, Can-ada, Winnipeg) ,  Mehdi Eshragi (Dep. of Biochemistry and Medical Genetics, Manitoba Inst. of Cell Biology, CancerCare Manitoba, Canada, Winnipeg) ,  Sudharsana R Ande (Dep. of Biochemistry and Medical Genetics, Manitoba Inst. of Cell Biology, CancerCare Manitoba, Canada, Winnipeg) ,  Walter J Chazin (Dep. of Biochemistry and Chemistry, Center for Structural Biology, Vanderbilt Univ., USA, Nashville) ,  Thomas Klonisch (Dep. of Human Anatomy and Cell Sci., Univ. of Manitoba, Canada, Winnipeg) ,  Andrew J Halayko (Dep. of Physiology, Univ. of Manitoba, Canada, Winnipeg) ,  Karol D Mcneill (Manitoba Inst. of Child Health, Univ. of Manitoba, Canada, Winnipeg) ,  Mohammad Hashemi (Dep. of Clinical Biochemistry, Zahedan Univ. of Medical Sciences, Iran, Zahedan) ,  Claus Kerkhoff (Inst. of Immunology, Universi-ty of Muenster, Germany, Muenster) ,  Marek Los (Interfaculty Inst. of Biochemistry, Univ. of Tubingen, Germany, Tubingen)
Material： Cell Research  (Cell Res)
Volume： 20  Issue： 3  Page： 314-331  Publication year： 2010 
JST Material Number： C2561A  ISSN： 1001-0602  Document type： Article
Article type： 原著論文  Country of issue： United Kingdom (GBR)  Language： ENGLISH (EN)

Thesaurus term： *S-100 protein ,  transmembrane protein ,  Mitochondria ,  lysosome ,  active oxygen ,  *Phagocytosis ,  *Apoptosis ,  *protein complex ,  tumor suppressor protein ,  gene expression ,  Proteins ,  membrane potential ,  fatty acid ,  aliphatic amine ,  thiol ,  carboxamide ,  sulfur containing amino acid ,  macrocyclic compound ,  lactone ,  conjugated diene ,  unsaturated carboxylic acid ,  phenol ether ,  diol ,  secondary alcohol ,  *Autophagy ,  Bnip3 protein ,  *S100A8 protein ,  *S100A9 protein ,  Membrane Potential, Mitochondrial ,  overexpression ,  Beclin-1 ,  molecular genetic phenomenon
Semi thesaurus term： Atg12 protein ,  Atg5 protein

JST classification (2)： Cell physiology in general  (EF02010S) ,  Biological function  (EB03040U)

Substance index (3)： 3-Methyladenine ,  Acetylcysteine ,  Bafilomycin A1

Terms in the title (10)： S100A8 ,  Bnip3 ,  ミトコンドリア ,  リソソーム ,  ROS ,  仲介 ,  クロストーク ,  オートファジー ,  アポトーシス ,  誘導