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J-GLOBAL ID：201102258014171387   Reference number：11A0679864

miR-182-Mediated Downregulation of BRCA1 Impacts DNA Repair and Sensitivity to PARP Inhibitors

BRCA1のmiR-182-介在ダウンレギュレーションはDNA修復及びPARP阻害剤に対する感受性に影響する

Author (16)： MOSKWA Patryk (Dep. of Radiation Oncology, Dana Farber Cancer Inst., Harvard Medical School, Boston, MA 02115, USA) ,  BUFFA Francesca M. (Cancer Res. UK Dep. of Medical Oncology, Univ. of Oxford, Weatherall Inst. of Molecular Medicine, John Radcliffe ...) ,  PAN Yunfeng (Dep. of Radiation Oncology, Dana Farber Cancer Inst., Harvard Medical School, Boston, MA 02115, USA) ,  PANCHAKSHARI Rohit (Dep. of Radiation Oncology, Dana Farber Cancer Inst., Harvard Medical School, Boston, MA 02115, USA) ,  GOTTIPATI Ponnari (Cancer Res. UK-Medical Res. Council Gray Inst. for Radiation Oncology and Biology, Univ. of Oxford, Oxford OX3 7DQ, GBR) ,  MUSCHEL Ruth J. (Cancer Res. UK-Medical Res. Council Gray Inst. for Radiation Oncology and Biology, Univ. of Oxford, Oxford OX3 7DQ, GBR) ,  BEECH John (Cancer Res. UK-Medical Res. Council Gray Inst. for Radiation Oncology and Biology, Univ. of Oxford, Oxford OX3 7DQ, GBR) ,  KULSHRESTHA Ritu (Dep. of Radiation Oncology, Dana Farber Cancer Inst., Harvard Medical School, Boston, MA 02115, USA) ,  ABDELMOHSEN Kotb (Lab. of Cellular and Molecular Biology, NIA-IRP, NIH, Baltimore, MD 21224, USA) ,  WEINSTOCK David M. (Dep. of Medical Oncology, Dana Farber Cancer Inst., Harvard Medical School, Boston, MA 02115, USA) ,  GOROSPE Myriam (Lab. of Cellular and Molecular Biology, NIA-IRP, NIH, Baltimore, MD 21224, USA) ,  HARRIS Adrian L. (Cancer Res. UK Dep. of Medical Oncology, Univ. of Oxford, Weatherall Inst. of Molecular Medicine, John Radcliffe ...) ,  HELLEDAY Thomas (Cancer Res. UK-Medical Res. Council Gray Inst. for Radiation Oncology and Biology, Univ. of Oxford, Oxford OX3 7DQ, GBR) ,  HELLEDAY Thomas (Dep. of Genetics Microbiology and Toxicology, Stockholm Univ., S-106 91 Stockholm, SWE) ,  HELLEDAY Thomas (Sci. for Life Lab., Stockholm Univ., Box 1031, SE-171 21 Solna, SWE) ,  CHOWDHURY Dipanjan (Dep. of Radiation Oncology, Dana Farber Cancer Inst., Harvard Medical School, Boston, MA 02115, USA)
Material： Molecular Cell  (Mol Cell)
Volume： 41  Issue： 2  Page： 210-220  Publication year： Jan. 21, 2011 
JST Material Number： W1167A  ISSN： 1097-2765  Document type： Article
Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Terms in the title (5)： BRCA1 ,  ダウンレギュレーション ,  DNA修復 ,  PARP阻害剤 ,  感受性