Art

J-GLOBAL ID：201102261864463515   Reference number：11A1433565

Induction of TK mutations in human lymphoblastoid TK6 cells by the rat carcinogen 3-chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone (MX)

ラット発がん物質3-クロロ-4-(ジクロロメチル)-5-ヒドロキシ-2(5H)-フラノン(MX)によるヒトリンパ芽球TK6細胞におけるTK突然変異の誘導

Author (6)： HAKULINEN Pasi (Div. of Genetics and Mutagenesis, National Inst. of Health Sciences, 1-18-1 Kamiyoga, Setagaya-ku, Tokyo 158-8501, JPN) ,  YAMAMOTO Ayumi (Div. of Genetics and Mutagenesis, National Inst. of Health Sciences, 1-18-1 Kamiyoga, Setagaya-ku, Tokyo 158-8501, JPN) ,  KOYAMA Naoki (Div. of Genetics and Mutagenesis, National Inst. of Health Sciences, 1-18-1 Kamiyoga, Setagaya-ku, Tokyo 158-8501, JPN) ,  KUMITA Wakako (Div. of Genetics and Mutagenesis, National Inst. of Health Sciences, 1-18-1 Kamiyoga, Setagaya-ku, Tokyo 158-8501, JPN) ,  YASUI Manabu (Div. of Genetics and Mutagenesis, National Inst. of Health Sciences, 1-18-1 Kamiyoga, Setagaya-ku, Tokyo 158-8501, JPN) ,  HONMA Masamitsu (Div. of Genetics and Mutagenesis, National Inst. of Health Sciences, 1-18-1 Kamiyoga, Setagaya-ku, Tokyo 158-8501, JPN)
Material： Mutation Research  (Genetic Toxicology and Environmental Mutagenesis)
Volume： 725  Issue： 1-2  Page： 43-49  Publication year： Oct. 09, 2011 
JST Material Number： C0520A  ISSN： 0027-5107  CODEN： MRFMEC  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Thesaurus term： *carcinogen ,  lymphocyte ,  blast cell ,  comet assay ,  micronucleus test ,  thymidine kinase ,  *mutation ,  DNA lesion ,  nucleotide sequence ,  LOH ,  tumor cell ,  cultured cell
Semi thesaurus term： TK6 cell ,  lymphoblast ,  heterozygosity

JST classification (1)： Influence on animals  (EE05040R)

Substance index (1)： 3-Chloro-4-dichloromethyl-5-hydroxy-2(5H)-furanone

Terms in the title (7)： ラット ,  発がん物質 ,  ヒト ,  リンパ芽球 ,  TK6細胞 ,  突然変異 ,  誘導