Art

J-GLOBAL ID：201102263111861740   Reference number：11A1269955

Metronomic doxifluridine chemotherapy combined with the anti-angiogenic agent TNP-470 inhibits the growth of human uterine carcinosarcoma xenografts

抗血管新生薬TNP-470を併用するドキシフルリジンのメトロノミックケモセラピーはヒト子宮癌肉腫異種移植片の増殖を阻害する

Author (9)： NAGANUMA Yasuko (Fukuoka Univ., Fukuoka) ,  CHOIJAMTS Batsuren (Fukuoka Univ., Fukuoka) ,  SHIROTA Kyoko (Fukuoka Univ., Fukuoka) ,  NAKAJIMA Kyoko (Fukuoka Univ., Fukuoka) ,  OGATA Shigenori (Fukuoka Univ., Fukuoka) ,  MIYAMOTO Shingo (Fukuoka Univ., Fukuoka) ,  KAWARABAYASHI Tatsuhiko (Fukuoka Univ., Fukuoka) ,  EMOTO Makoto (Fukuoka Univ., Fukuoka) ,  EMOTO Makoto (Fukuoka Sanno Hospital, Fukuoka, JPN)
Material： Cancer Science  (Cancer Sci)
Volume： 102  Issue： 8  Page： 1545-1552  Publication year： Aug. 2011 
JST Material Number： W1423A  ISSN： 1347-9032  Document type： Article
Article type： 原著論文  Country of issue： Australia (AUS)  Language： ENGLISH (EN)

Thesaurus term： experimental disease ,...
Semi thesaurus term： FU-MMT-1細胞 ,...

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JST classification (3)： Basic oncology in general  (GE02010R) ,  Basic therapeutics  (GC03012A) ,  Basic research of antitumor(=antineoplastic)drugs  (GW16010A)

Substance index (2)： TNP-470 ,  5'-DFUR

Reference (34)：

• SARTORI, E. Carcinosarcoma of the uterus : a clinicopathological multicenter CTF study. Gynecol Oncol. 1997, 67, 70-75
• MILLER, BE. A phase II evaluation of weekly gemcitabine and docetaxel for second-line treatment of recurrent carcinosarcoma of the uterus : a gynecologic oncology group study. Gynecol Oncol. 2010, 118, 139-144
• EMOTO, M. Angiogenesis in carcinosarcomas of the uterus : differences in the microvessel density and expression of vascular endothelial growth factor between the epithelial and mesenchymal elements. Hum Pathol. 1999, 30, 1232-1241
• EMOTO, M. Localization of the VEGF and angiopoietin genes in uterine carcinosarcoma. Gynecol Oncol. 2004, 95, 474-482
• HOLASH, J. Vessel cooption, regression, and growth in tumors mediated by angiopoietins and VEGF. Science. 1999, 284, 1994-1998

Terms in the title (10)： 抗血管新生薬 ,  TNP-470 ,  併用 ,  ドキシフルリジン ,  メトロノミックケモセラピー ,  ヒト ,  子宮癌肉腫 ,  異種移植片 ,  増殖 ,  阻害