Screening of promising chemotherapeutic candidates against human adult T-cell leukemia/lymphoma from plants: active principles from Physalis pruinosa and structure-activity relationships with withanolides

NAKANO Daisuke; ISHITSUKA Kenji; HATSUSE Takahiro; TSUCHIHASHI Ryota; OKAWA Masafumi; OKABE Hikaru; TAMURA Kazuo; KINJO Junei

Art

J-GLOBAL ID：201102272673491529 Reference number：11A1162453

Screening of promising chemotherapeutic candidates against human adult T-cell leukemia/lymphoma from plants: active principles from Physalis pruinosa and structure-activity relationships with withanolides

植物由来ヒト成人T細胞白血病/リンパ腫に対する有望な化学療法候補のスクリーニング:Physalis pruinosaの有効成分とウィタノリド類との構造活性相関

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Material：
Volume： 65 Issue： 3/4 Page： 559-567 Publication year： 2011
JST Material Number： L5856A ISSN： 1340-3443 Document type： Article
Article type：原著論文 Country of issue： Germany, Federal Republic of (DEU) Language： ENGLISH (EN)

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Basic research of pharmacology of crude drugs , Basic research of antitumor(=antineoplastic)drugs

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Reference (22)：

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NAGAO, T. Anti-proliferative phenolic constituents in plants and structure-activity relationships. FFI J. 2004, 209, 2-12
TAKATSUKI, K. Surface markers of malignant lymphoid cells in the classification of lymphoproliferative disorders, with special reference to adult T-cell leukemia. Rinsho Ketsueki. 1976, 17, 416-421
UCHIYAMA, T. Adult T-cell leukemia : clinical and hematologic features of 16 cases. Blood. 1977, 50, 481-492
POIESZ, BJ. Detection and isolation of type C retrovirus particles from fresh and cultured lymphocytes of a patient with cutaneous T-cell lymphoma. Proc Natl Acad Sci USA. 1980, 77, 7415-7419

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