Art

J-GLOBAL ID：201102288815949904   Reference number：11A0527562

Interleukin-19 Is a Negative Regulator of Innate Immunity and Critical for Colonic Protection

インターロイキン-19は自然免疫の負の調節因子であり結腸保護にとって重要である

Author (8)： AZUMA Yasu-taka (Lab. of Veterinary Pharmacology, Div. of Veterinary Sci., Osaka Prefecture Univ. Graduate School of Life and ...) ,  MATSUO Yukiko (Lab. of Veterinary Pharmacology, Div. of Veterinary Sci., Osaka Prefecture Univ. Graduate School of Life and ...) ,  NAKAJIMA Hidemitsu (Lab. of Veterinary Pharmacology, Div. of Veterinary Sci., Osaka Prefecture Univ. Graduate School of Life and ...) ,  YANCOPOULOS George D. (Regeneron Pharmaceuticals, Inc., USA) ,  VALENZUELA David M. (Regeneron Pharmaceuticals, Inc., USA) ,  MURPHY Andrew J. (Regeneron Pharmaceuticals, Inc., USA) ,  KAROW Margaret (Regeneron Pharmaceuticals, Inc., USA) ,  TAKEUCHI Tadayoshi (Lab. of Veterinary Pharmacology, Div. of Veterinary Sci., Osaka Prefecture Univ. Graduate School of Life and ...)
Material： Journal of Pharmacological Sciences  (J Pharmacol Sci)
Volume： 115  Issue： 2  Page： 105-111 (J-STAGE)  Publication year： 2011 
JST Material Number： G0813A  ISSN： 1347-8613  Document type： Article
Article type： 解説  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *interleukin ,...
Semi thesaurus term： B lymphocyte ,...

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JST classification (3)： Cytokines  (EB08090G) ,  Digestive system diseases  (GH03000W) ,  Biophylaxis and immune systems in general  (ED01010F)

Reference (50)：

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• ELSON, CO. Experimental models of inflammatory bowel disease reveal innate, adaptive, and regulatory mechanisms of host dialogue with the microbiota. Immunol Rev. 2005, 206, 260-276
• BRAAT, H. Interieukin-10-based therapy for inflammatory bowel disease. Expert Opin Biol Ther. 2003, 3, 725-731
• LI, MC. IL-10 and its related cytokines for treatment of inflammatory bowel disease. World J Gastroenterol. 2004, 10, 620-625
• YAMAMOTO-FURUSHO, JK. Innovative therapeutics for inflammatory bowel disease. World J Gastroenterol. 2007, 13, 1893-1896

Terms in the title (4)： インターロイキン-19 ,  自然免疫 ,  調節因子 ,  結腸