Art

J-GLOBAL ID：201102290045336822   Reference number：11A1263146

GABA exerts protective and regenerative effects on islet beta cells and reverses diabetes

GABAは膵島β細胞に防御および再生効果を発揮して糖尿病を回復させる

Author (25)： SOLTANI Nepton (St. Michael’s Hospital, ON, CAN) ,  SOLTANI Nepton (Univ. Toronto, ON, CAN) ,  QIU Hongmin (St. Michael’s Hospital, ON, CAN) ,  QIU Hongmin (Univ. Toronto, ON, CAN) ,  ALEKSIC Mila (Univ. Toronto, ON, CAN) ,  GLINKA Yelena (St. Michael’s Hospital, ON, CAN) ,  ZHAO Fang (St. Michael’s Hospital, ON, CAN) ,  ZHAO Fang (Univ. Toronto, ON, CAN) ,  LIU Rui (St. Michael’s Hospital, ON, CAN) ,  LIU Rui (Fudan Univ., Shanghai, CHN) ,  LI Yiming (Fudan Univ., Shanghai, CHN) ,  ZHANG Nina (St. Michael’s Hospital, ON, CAN) ,  ZHANG Nina (Univ. Toronto, ON, CAN) ,  CHAKRABARTI Rabindranath (Fudan Univ., Shanghai, CHN) ,  NG Tiffany (St. Michael’s Hospital, ON, CAN) ,  NG Tiffany (Univ. Toronto, ON, CAN) ,  JIN Tianru (Univ. Toronto, ON, CAN) ,  ZHANG Haibo (St. Michael’s Hospital, ON, CAN) ,  ZHANG Haibo (Univ. Toronto, ON, CAN) ,  LU Wei-Yang (Univ. Western Ontario, ON, CAN) ,  FENG Zhong-Ping (Univ. Toronto, ON, CAN) ,  PRUD'HOMME Gerald J. (St. Michael’s Hospital, ON, CAN) ,  WANG Qinghua (St. Michael’s Hospital, ON, CAN) ,  WANG Qinghua (Univ. Toronto, ON, CAN) ,  WANG Qinghua (Fudan Univ., Shanghai, CHN)
Material： Proceedings of the National Academy of Sciences of the United States of America  (PNAS)
Volume： 108  Issue： 28  Page： 11692-11697  Publication year： Jul. 12, 2011 
JST Material Number： D0387A  ISSN： 0027-8424  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Thesaurus term： mouse(animal) ,  experimental disease ,  hypoglycemic drug ,  immunosuppressive action ,  GABAA receptor ,  cellular signal transduction ,  endocrine cell ,  Langerhans islet ,  protective action ,  aliphatic amine ,  aliphatic carboxylic acid ,  aminocarboxylic acid ,  primary amine ,  *type 1 diabetes mellitus
Semi thesaurus term： *insulin-dependend diabetes mellitus ,  pancreatic beta cell

JST classification (1)： Basic research of drugs acting on carbohydrate metabolism  (GW13020Q)

Substance index (1)： GABA

Terms in the title (6)： GABA ,  膵島 ,  β細胞 ,  防御 ,  糖尿病 ,  回復