Art

J-GLOBAL ID：201102295786868785   Reference number：10A1755607

Metabonomic study on ‘Kidney-Yang Deficiency syndrome’ and intervention effects of Rhizoma Drynariae extracts in rats using ultra performance liquid chromatography coupled with mass spectrometry

質量分析と組み合わせた超高速液体クロマトグラフィーを用いたラットでの「腎臓-Yang不全症候群」およびRhizoma Drynariae抽出物の介入効果に関するメタボノミクス研究

Author (6)： LU Xiumei (Dep. of Analytical Chemistry, Shenyang Pharmaceutical Univ., 103 Wenhua Road, Shenyang 110016, CHN) ,  XIONG Zhili (Dep. of Analytical Chemistry, Shenyang Pharmaceutical Univ., 103 Wenhua Road, Shenyang 110016, CHN) ,  LI Jingjing (Dep. of Analytical Chemistry, Shenyang Pharmaceutical Univ., 103 Wenhua Road, Shenyang 110016, CHN) ,  ZHENG Shuning (Dep. of Analytical Chemistry, Shenyang Pharmaceutical Univ., 103 Wenhua Road, Shenyang 110016, CHN) ,  HUO Taoguang (Dep. of Analytical Chemistry, Shenyang Pharmaceutical Univ., 103 Wenhua Road, Shenyang 110016, CHN) ,  LI Famei (Dep. of Analytical Chemistry, Shenyang Pharmaceutical Univ., 103 Wenhua Road, Shenyang 110016, CHN)
Material： Talanta  (International Journal of Pure and Applied Analytical Chemistry)
Volume： 83  Issue： 3  Page： 700-708  Publication year： Jan. 15, 2011 
JST Material Number： E0324A  ISSN： 0039-9140  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Thesaurus term： *metabolite ,  *HPLC-MS analysis ,  *renal insufficiency ,  urine analysis ,  *Chinese drug ,  rat ,  principal component analysis ,  *urinary excretion ,  drug metabolism ,  amino acid ,  nitrogen heterocyclic compound ,  aliphatic alcohol ,  aliphatic carboxylic acid ,  hydroxy acid ,  polycarboxylic acid ,  lactam ,  steroid ,  enone ,  alicyclic alcohol ,  alicyclic ketone ,  diketone ,  secondary alcohol ,  hydroxy ketone ,  polyol ,  aromatic compound ,  primary amine ,  aromatic carboxylic acid ,  carboxamide ,  glucocorticoid
Semi thesaurus term： Rhizoma Drynariae ,  メタボノミクス ,  腎臓-Yang不全症候群 ,  ultra performance liquid chromatography-mass spectrometry

JST classification (3)： Miscellaneous analytical methods of organic compounds  (CC08034J) ,  Basic biopharmacy  (GY01021U) ,  Crude drugs in general  (GX06010Y)

Substance index (8)： Proline ,  N2-Succinyl-L-ornithine ,  Citric acid ,  Creatinine ,  Cortisol ,  N-(Phenylacetyl)glycine ,  Phenylalanine ,  Hippuric acid

Terms in the title (9)： 質量分析 ,  高速液体クロマトグラフィー ,  ラット ,  腎臓 ,  症候群 ,  抽出物 ,  介入効果 ,  メタボノミクス ,  研究