Research Resource code：5000000396
Update date：Nov. 10, 2004
Effect of in ovo exposure of DES and aromatase inhibitor on sex determination and gonad in checkens
Bibliographic database (Bibliography, Abstract, Full text)
Diethylstilbestrol (DES) or aromatase inhibitors (AI)
Return to Previous Page
of 0.1 mg was injected into the egg albumen of a
fertilized hen egg.
After hatching, the sex was determined. As the result,
about 44 % of the DES injected group was male by the
genetic sexual determination, while 100 % was female by
the phenotypic sexual determination.
On the other hand, about 40 % of the AI injected group
was female by the genetic sexual determination,
while 100 % was female by the phenotypic sexual
Thus, it is clear that the sexual inconsistency (sexual
disruption) between the phenotypic sex and genetic
sex is induced by chemical substances to affect the
sexual differentiation and that the aromatase activity
of genital glands changes noticeably.