J-GLOBAL ID:201201001066088677   Update date: Apr. 03, 2024

Sasaki Kazunori

ササキ カズノリ | Sasaki Kazunori
Affiliation and department:
Homepage URL  (1): https://ycu-molecularbiology.jp
Research field  (6): Medical biochemistry ,  Cell biology ,  Molecular biology ,  Anatomy ,  General surgery, pediatric surgery ,  Urology
Research keywords  (28): cell polarity ,  細胞接着 ,  kinase ,  aPKC ,  PAR-3 ,  タイトジャンクション ,  stem cell ,  progenitor ,  シグナル伝達 ,  G protein ,  Guanine nucleotide exchange factor ,  GEF ,  Girdin ,  heterotrimeric G protein ,  Galphai ,  低分子量Gタンパク質 ,  Rap1 ,  Shank2 ,  遺伝子発現 ,  転写 ,  mammary gland ,  breast cancer ,  transcripion factor ,  Transplantation ,  cell growth ,  cell differentiation ,  organoid ,  sphere
Papers (27):
  • Matsuoka I, Kasai T, Onaga C, Ozaki A, Motomura H, Maemura Y, Tada Y, Mori H, Hara Y, Xiong Y, et al. Co-expression of SLC20A1 and ALDH1A3 is associated with poor prognosis, and SLC20A1 is required for the survival of ALDH1-positive pancreatic cancer stem cells. Oncology Letters. 2024. in press
  • Ozaki A, Matsuda A, Maemura Y, Tada Y, Kasai T, Nagashima Y, Onaga C, Hara Y, Kitabatake K, Tsukimoto M, et al. Luminal B breast cancer coexpressing p62 and ALDH1A3 is less susceptible to radiotherapy. Anticancer Research. 2024. 44. 1. 37-47
  • Takahiro Kasai, Shoma Tamori, Yuta Takasaki, Izumi Matsuoka, Ayaka Ozaki, Chika Matsuda, Yohsuke Harada, Kazunori Sasaki, Shigeo Ohno, Kazunori Akimoto. High expression of PKCλ and ALDH1A3 indicates a poor prognosis, and PKCλ is required for the asymmetric cell division of ALDH1A3-positive cancer stem cells in PDAC. Biochemical and biophysical research communications. 2023. 669. 85-94
  • Okamoto T, Onaga C, Matsuoka I, Ozaki A, Matsuda C, Kasai T, Xiong Y, Harada Y, Sato T, Nakano Y, et al. High SLC20A1 Expression Indicates Poor Prognosis in Prostate Cancer. Cancer Diagn Progn. 2023. 3. 4. 439-448
  • Xiong Y, Motomura H, Tamori S, Ozaki A, Onaga C, Hara Y, Sato K, Tahata K, Harada Y, Sasaki K, et al. High Expression of CD58 and ALDH1A3 Predicts a Poor Prognosis in Basal-like Breast Cancer. Anticancer Research. 2022. 42. 11. 5223-5232
MISC (7):
Books (1):
  • 翻訳後修飾のプロテオミクス
    講談社 2011
Lectures and oral presentations  (55):
  • 乳がんサブタイプにおけるaPKC遺伝子発現と放射線および薬物治療との関連性の解析
    (日本薬学会第144年会 2024)
  • Identification of prognostic genes related to nuclear localized aPKCλ/ι in cervical squamous cell carcinoma
    (The 10th International Postgraduate Conference on Pharmaceutical Sciences (iPoPS2024) 2024)
  • Analysis of the acquisition mechanism of cancerous heterogeneity generating by asymmetric cell division of cancer stem cells
    (The 10th International Postgraduate Conference on Pharmaceutical Sciences (iPoPS2024) 2024)
  • Screening of natural compounds regulating in vitro tumor-sphere formation of ALDH1 positive cancer stem cells
    (The 10th International Postgraduate Conference on Pharmaceutical Sciences (iPoPS2024) 2024)
  • Analysis of PKCλ-dependent expression of glycolysis related molecules in triple-negative breast cancer
    (The 10th International Postgraduate Conference on Pharmaceutical Sciences (iPoPS2024) 2024)
Awards (1):
  • 2023/06 - (順天堂大学 大学院医学研究科 環境医学研究所) 第20回環境医学研究所プロジェクト研究報告会 最優秀ポスター賞
Association Membership(s) (2):
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