Rchr
J-GLOBAL ID:201201001307465132
Update date: Oct. 26, 2024
Kuroda Keisuke
クロダ ケイスケ | Kuroda Keisuke
Affiliation and department:
Job title:
Designated Associate Professor
Research field (5):
Molecular biology
, Cell biology
, Psychiatry
, Pharmacology
, Neuroscience - general
Research keywords (9):
Small GTPase
, Signal transduction
, DISC1
, Psychiatry
, Cell Biology
, Biochemistry
, dopamine
, schizophrenia
, 包括脳ネットワーク
Research theme for competitive and other funds (7):
- 2020 - 2023 Cell type specific analysis of intracellular signal in antipsychotics
- 2018 - 2022 Analysis of RhoA/Rho-kinase signals in neuronal circuit
- 2017 - 2021 Study on regulatory mechanism of neural activity and emotional behavior by intracellular signals
- 2016 - 2019 Elucidation of regulation mechanism of gene expression and emotional memory by dopamine signal
- 2015 - 2019 Cell type specific analysis of intracellular signal in neural circuit
- 2013 - 2016 Elucidation of phosphorylation signal regulating the cell polarity
- 2013 - 2015 Re-evaluation of DISC1 using knockout mice and new antibodies
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Papers (57):
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Yasuhiro Funahashi, Rijwan Uddin Ahammad, Xinjian Zhang, Emran Hossen, Masahiro Kawatani, Shinichi Nakamuta, Akira Yoshimi, Minhua Wu, Huanhuan Wang, Mengya Wu, et al. Signal flow in the NMDA receptor-dependent phosphoproteome regulates postsynaptic plasticity for aversive learning. Science signaling. 2024. 17. 853. eado9852
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Daisuke Tsuboi, Takeshi Otsuka, Takushi Shimomura, Md Omar Faruk, Yukie Yamahashi, Mutsuki Amano, Yasuhiro Funahashi, Keisuke Kuroda, Tomoki Nishioka, Kenta Kobayashi, et al. Dopamine drives neuronal excitability via KCNQ channel phosphorylation for reward behavior. Cell reports. 2022. 40. 10. 111309-111309
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Funahashi Yasuhiro, Ahammad Rijwan Uddin, Zhang Xinjian, Emran Hossen, Faruk Md. Omar, Wang Huanhuan, Wu Minhua, Xu Yifan, Tsuboi Daisuke, Nishioka Tomoki, et al. NMDA-induced activation of the CaMKII-RhoA-Rho-kinase pathway regulates aversive learning. Proceedings for Annual Meeting of The Japanese Pharmacological Society. 2022. 96. 2-B-P-109
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You-Hsin Lin, Yukie Yamahashi, Keisuke Kuroda, Md. Omar Faruk, Xinjian Zhang, Kiyofumi Yamada, Akihiro Yamanaka, Taku Nagai, Kozo Kaibuchi. Accumbal D2R-medium spiny neurons regulate aversive behaviors through PKA-Rap1 pathway. Neurochemistry International. 2021. 143. 104935-104935
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Nagaoka, K., Nagashima, T., Asaoka, N., Yamamoto, H., Toda, C., Kayanuma, G., Siswanto, S., Funahashi, Y., Kuroda, K., Kaibuchi, K., et al. Striatal TRPV1 activation by acetaminophen ameliorates dopamine D2 receptor antagonist-induced orofacial dyskinesia. JCI Insight. 2021. 6. 10
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MISC (21):
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Wulaer, B, Nagai T, Sobue, A, Itoh, N, Kuroda, K, Kaibuchi, K, Nabeshima, T, Yamada, K. Repetitive and compulsive-like behaviors lead to cognitive dysfunction in Disc1Δ2-3/Δ2-3 mice. Gene Brain Behav. 2018. e12478
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黒田啓介. To understand the molecular mechanism of psychiatric disorders. Analysis of dopaminergic intracellular signaling. 日本生物学的精神医学会誌. 2017. 28. 3. 127-131-131
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Y. Funahashi, A. Ariza, K. Suzuki, S. Wei, S. Kozawa, T. Takano, K. Kuroda, T. Nagai, K. Kaibuchi. Dopamine-induced phosphorylation of NPAS4 through MAPK regulates reward-related learning and memory. JOURNAL OF NEUROCHEMISTRY. 2017. 142. 129-129
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K. Kaibuchi, K. Kuroda, M. Yoshikawa. Phosphorylation signals in hippocampal and striatal synapses. JOURNAL OF NEUROCHEMISTRY. 2017. 142. 22-22
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Keisuke Kuroda, Taku Nagai, Mutsuki Amano, Junichiro Yoshimoto, Takayuki Kannon, Tomoki Nishioka, Shiro Usui, Kozo Kaibuchi. KANPHOS (Kinase-Associated Phospho-Signaling) Platform - A database for neural phosphoproteomics with quality control. JOURNAL OF PHARMACOLOGICAL SCIENCES. 2017. 133. 3. S263-S263
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Education (2):
- 2006 - 2010 Nagoya University Graduate School of Medicine
- 1998 - 2004 Nagoya University School of Medicine
Professional career (1):
- Doctor of Philosophy (Medical Science) (Nagoya University)
Work history (3):
- 2021/04 - 現在 Nagoya University Graduate School of Medicine Designated Associate Professor
- 2012/01 - 2021/03 Nagoya University Graduate School of Medicine Designated Assistant Professor
- 2010/04 - 2011/12 Nagoya University Graduate School of Medicine guest researcher
Association Membership(s) (4):
Society for Neuroscience
, THE JAPANESE PHARMACOLOGICAL SOCIETY
, THE JAPAN NEUROSCIENCE SOCIETY
, THE JAPANESE SOCIETY FOR NEUROCHEMISTRY
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