Inoue Koichi

Affiliation and department：

Research field (3)： Neuroscience - general , Psychiatry , Anesthesiology

Research keywords (30)：発達 , cell sorting , 脳 , マイクロアレイ , 移動 , 神経 , GABA , 細胞移動 , クロライドトランスポーター , カハールレチウス細胞 , 国際情報交換 , ドイツ , タウリン , 皮質板細胞 , グリシン , てんかん , イメージング , 皮質形成異常 , クロライドイオン , 大脳皮質 , Cl^-ホメオスタシス , Chrolide , プリン受容体 , 小脳 , 肝細胞癌 , 生物進化 , 電気穿孔法 , 言語 , クロラドトランスポーター , 化学発癌

Research theme for competitive and other funds (25)：

2021 - 2024 Novel tumor suppression system targeting microglia, considering glioma/microglia correlation
2018 - 2021 Molecular biological approaches in the treatment of ASIC1a locomotive syndrome.
2016 - 2021 Creation and Promotion of Willdynamics
2016 - 2021 The neuroendocrine system, as seen from gut peptides: The expression of emotional and social behaviors, and fluctuations and changes in mood
2016 - 2019 Optogenetical regulation of eNOS activity and vascular function

2011 - 2013 The role of ambient GABA in cerebelllar foliation

2011 - 2012 カハール・レチウス細胞等のGABAの積極的興奮性とその生理的意義の解明

2010 - 2012 Developmentaldisorder of fetal GABA system by maternal stress

2011 - 2011 Perturbation of developmental Cl^-homeodynamics may underlie fetal and neonatal brain disorders

2011 - 2011 タウリンによるKCC2活性制御の分子基盤とその意義の解明

2008 - 2010 Visualization of changes in intracellular ions during glioma cell migration

2005 - 2006 分子標的発見による肝臓強化新療法の基礎的研究

2005 - 2006 Exhaustive detection and analysis of gene expression associated with radial migration and differentiation in developing neocortical neurons

2004 - 2006 Environmental influences on cortical development and plasticity via Cl^-homeostasis modulation

2005 - 2005 大脳皮質回路形成過程の細胞間クロストークにおけるGABAとタウリンの役割

2005 - 2005 会話言語遺伝子FOXP2の高次脳機能における役割の解明

2005 - 2005 フォークヘッド遺伝子Foxc2による乳癌細胞転移促進作用とその分子機構の解明

2004 - 2005 Establishment of trigeminal neuralgia model and role of ATP receptor for neuropathic pain

2004 - 2005 細胞外Cl^-を調節して神経回路の興奮性を制御するグリアのCl^-トランスポーター

2004 - 2004 大脳皮質形成期の接線方向移動と放射状移動の細胞間クロストークにおけるCl^-の役割

2003 - 2004 Cl^-homeostasis failure and abnormal cell migration by endocrine disruptor cause damage to nervous system

2002 - 2004 てんかん原性皮質形成異常におけるCl^-ホメオスタシスとGABA機能異常の分子機構

2003 - 2003 大脳新皮質形成過程におけるカハール・レチウス細胞と皮質板細胞のクロストーク

2000 - 2003 An approach for anti-sense therapy based on the establishment of an animal model for the epileptogenic cortical malformations

2002 - 2002 大脳新皮質形成過程におけるカハール・レチウス細胞と皮質板細胞のクロストーク

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Papers (56)：

Noriko Horii-Hayashi, Kazuya Masuda, Taika Kato, Kenta Kobayashi, Ayumu Inutsuka, Miyu F. Nambu, Kazumasa Z. Tanaka, Koichi Inoue, Mayumi Nishi. Entrance-sealing behavior in the home cage: a defensive response to potential threats linked to the serotonergic system and manifestation of repetitive/stereotypic behavior in mice. Frontiers in Behavioral Neuroscience. 2024. 17
Shinnosuke Koketsu, Kohki Matsubara, Yoshino Ueki, Yoshiaki Shinohara, Koichi Inoue, Satona Murakami, Takatoshi Ueki. The defects of the hippocampal ripples and theta rhythm in depression, and the effects of physical exercise on their amelioration. Heliyon. 2024. 10. 1. e23738-e23738
Tomoyasu Yamanaka, Takatoshi Ueki, Mitsuhito Mase, Koichi Inoue. Arbitrary Ca2+ regulation for endothelial nitric oxide, NFAT and NF-κB activities by an optogenetic approach. Frontiers in Pharmacology. 2023. 13
Atsuhiko Okura, Koichi Inoue, Eisuke Sakuma, Hiroshi Takase, Takatoshi Ueki, Mitsuhito Mase. SGK1 in Schwann cells is a potential molecular switch involved in axonal and glial regeneration during peripheral nerve injury. Biochemical and Biophysical Research Communications. 2022. 607. 158-165
Koichi Inoue. Potential significance of CX3CR1 dynamics in stress resilience against neuronal disorders. Neural Regeneration Research. 2022. 17. 10. 2153-2153

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MISC (16)：

若林健二郎, 佐久間英輔, 植木孝俊, 大塚隆信, 和田郁雄, 水谷潤, 植木美乃, 村上里奈, 青山公紀, 井上浩一, et al. ASIC1aノックアウトマウスの育児障害. 日本整形外科学会雑誌. 2016. 90. 8. S1589-S1589
Mingli Liu, Koichi Inoue, Zhi-gang Xiong. ASIC1 regulates neuronal differentiation of neuroblastoma through Notch signaling pathway. CANCER RESEARCH. 2016. 76
Mingli Liu, Koichi Inoue, An Zhou, Zhigang Xiong. ASIC1 impacts Notch signaling pathway in the neuronal differentiation of neuroblatoma. CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION. 2016. 25. 3
Mingli Liu, Koichi Inoue, Tiandong Leng, Shanchun Guo, Zhigang Xiong. TRPM7 channels regulate glioma stem cell through STAT3 and Notch signaling pathways. CANCER RESEARCH. 2014. 74. 19
Koichi Inoue, Tomonori Furukawa, Junko Yamada, Tatsuro Kumada, Tianying Wang, Rieko Inoue, Atsuo Fukuda. Developmental regulation of KCC2 activity by taurine in a phosphorylation-dependent manner. NEUROSCIENCE RESEARCH. 2011. 71. E130-E130

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Education (2)：

- 2002 東京医科歯科大学大学院医学系研究科
- 1996 名古屋市立大学医学部医学科

Work history (8)：

2023 - 現在 Nara Medical University
2017 - 名古屋市立大学医学研究科准教授
2015 - 名古屋市立大学医学研究科助教/講師
2012 - Morehouse School of Medicine
2010 - Hamamatsu University School of Medicine Faculty of Medicine

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