Rchr
J-GLOBAL ID:201201006952348118   Update date: Apr. 26, 2025

NOMURA Jun

ノムラ ジュン | NOMURA Jun
Affiliation and department:
Job title: Visiting Associate Professor
Homepage URL  (2): https://nrid.nii.ac.jp/en/nrid/1000070406528/https://jp.linkedin.com/in/jun-nomura-2683273a
Research field  (6): Neuroscience - general ,  Pharmaceuticals - health and biochemistry ,  Animals: biochemistry, physiology, behavioral science ,  Molecular biology ,  Psychiatry ,  Pathobiochemistry
Research keywords  (12): Mental Disorders ,  Developmental Disorders ,  Regenerative Medicine ,  Schizophrenia ,  Autism ,  Chromosome Engineering ,  Genome editing ,  Stem Cells ,  Knockout mouse ,  Gene Targeting ,  Differentiation ,  Oncogenicity
Research theme for competitive and other funds  (13):
  • 2024 - 2027 Phase-specific risk factor analysis of the translation process in autism
  • 2021 - 2024 Identifying drug targets for neuropsychiatric and neurodevelopmental disorders via brain transcriptome
  • 2018 - 2023 Integrated analysis of the human chromosome 15q13.3 copy number variation
  • 2017 - 2020 Develop and analysis for chromosome mutant mice
  • 2016 - 2017 RIKEN-MITI FS research fund
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Papers (34):
  • Sawako Furukawa*, Jun Nomura* (contributed equally), HIroaki Hanafusa, Hiroko Maegawa, Toru Takumi. Germ-cell-specific transcriptome analysis illuminates the chromatin and ubiquitin pathway in autism spectrum disorders. Autism Research. 2023. 16. 6. 1101-1110
  • Chia-Wen Lin, Dian E. Septyaningtrias, Hsu-Wen Chao, Mikiko Konda, Koji Atarashi, Kozue Takeshita, Kota Tamada, Jun Nomura, Yohei Sasagawa, Kaori Tanaka, et al. A common epigenetic mechanism across different cellular origins underlies systemic immune dysregulation in an idiopathic autism mouse model. Molecular Psychiatry. 2022. 27. 8. 3343-3354
  • Jun Nomura, Amila Zuko, Keiko Kishimoto, Hiroaki Mutsumine, Kazumi Fukatsu, Yoshiko Nomura, Xiaoxi Liu, Nobuhiro Nakai, Eiki Takahashi, Tsukasa Kouno, et al. Autism in a dish: ES cell models of autism with copy number variations reveal cell-type-specific vulnerability. BioRxiv. 2022
  • Yoshiko Nomura, Jun Nomura, Toru Nishikawa, Toru Takumi. Reciprocal differentiation via GABAergic components and ASD-related phenotypes in hES with 1q21.1 CNV. BioRrxiv. 2021
  • Jun Nomura, Matthew Mardo, Toru Takumi. Molecular signatures from multi-omics of autism spectrum disorders and schizophrenia. Journal of Neurochemistry. 2021. 159. 4. 647-659
more...
MISC (31):
  • Nomura J, Takumi T. Identification of cell type-specific autism risk factors by single-cell, organoid studies. Japanese Journal of Biological Psychiatry. 2022. 33. 2. 48-52
  • Jun Nomura, Toru Takumi. Emerging technologies for autism spectrum disorders. Japanese Journal of Biological Psychiatry. 2020. 31. 2. 71-75
  • Jun Nomura, Toru Takumi. Comprehensive analysis of the human chromosome 15q13.3 copy number variation. Smoking Research Foundation annual research report. 2019. 1132-1135
  • Jun Nomura, Toru Takumi. Trends in in vitro basic research for autism phenotyping. Journal of clinical and experimental medicine. 2019. 268. 3. 184-190
  • Mami Yamazaki, Toru Takumi, Jun Nomura, Kenzo Takahashi. Identification of a common mechanism for autism spectrum disorders caused by abnormal copy number variation. Ryukyu Medical Journal. 2017. 36. 1-2. 47-47
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Lectures and oral presentations  (109):
  • Cell-type specific pathology of microglia with autism-associated 1q21.1 copy number variations
    (APPW2025 The 130th Annual Meeting of the Japanese Association of Anatomists (JAA) The 102nd Annual Meeting of the Physiological Society of Japan (PSJ) The 98th Annual Meeting of the Japanese Pharmacological Society (JPS) 2025)
  • The abnormal transcriptional network of TCF4 in the 15q13.3 microdeletion syndrome
    (APPW2025 The 130th Annual Meeting of the Japanese Association of Anatomists (JAA) The 102nd Annual Meeting of the Physiological Society of Japan (PSJ) The 98th Annual Meeting of the Japanese Pharmacological Society (JPS) 2025)
  • 【Symposium】Neuroscience@Kobe
    (Symposium on Mental Disorders 2025)
  • Identification of key regulators of disease phenotypes associated with 15q13.3 deletion
    (The 13th Japan Emotionology Society 2024)
  • Disease phenotyping of microglia with 1q21.1 copy number polymorphism
    (The 13th Japan Emothionology Society 2024)
more...
Education (3):
  • 2002 - 2005 Hokkaido University Graduate School of Pharmaceutical Sciences
  • 1999 - 2001 Ritsumeikan University Graduate School of Science & Engineering
  • 1995 - 1999 Ritsumeikan University Science & Engineering Environmental Systems Engineering
Professional career (1):
  • Ph.D. (Pharmaceutical Sciences)
Work history (8):
  • 2025/04 - 現在 Kobe University Graduate School of Medicine Visiting Associate Professor
  • 2024/04 - 2025/03 Kobe University Graduate School of Medicine Lecturer
  • 2020/10 - 2024/03 Kobe University Graduate School of Medicine Assistant Professor
  • 2020/04 - 2020/09 Kobe University Graduate School of Medicine Specially Appointed Assistant Professor
  • 2016/04 - 2020/03 RIKEN Center for Brain Science Research Scientist
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Committee career (2):
  • 2018 - 現在 The International College of Neuropsychopharmacology (CINP) Fellow
  • 2016 - 現在 The Japanese Society of Neuropsychopharmacology Councilor
Awards (6):
  • 2023 - Journal of Neurochemistry (Wiley) Top Downloaded Article in Journal of Neurochemistry Molecular signatures from multi-omics of autism spectrum disorders and schizophrenia
  • 2022 - Neuroscience Research (Elsevier) Excellent Paper Award Transcriptome analysis of human neural cells derived from isogenic embryonic stem cells with 16p11.2 deletion.
  • 2020/01 - Takeda Science Foundation, The 10th Takeda Science Foundation International Symposium on PharmaSciences Excellent Poster Award
  • 2014 - RIKEN BSI Riken BSI Hot Topics 2014 Genome Editing Tools for Neurobiology
  • 2009 - International Congress on Schizophrenia Research (ICOSR), Young Investigator Program Award 2009, USA, A new cell model to study the mechanism of gene-environment interactions relevant to schizophrenia
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Association Membership(s) (9):
The Japanese Society for Bioinformatics ,  The Japanese Biochemical Society ,  The Molecular Biology Society of Japan ,  THE JAPANESE SOCIETY FOR NEUROCHEMISTRY ,  THE JAPAN NEUROSCIENCE SOCIETY ,  THE JAPANESE SOCIETY OF NEUROPSYCHOPHARMACOLOGY ,  International College of Neuropsychopharmacology ,  Society for Neuroscience ,  The International Behavioral Neuroscience Society (IBNS)
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