NOMURA Jun

ノムラジュン | NOMURA Jun

Affiliation and department：
Job title： Visiting Associate Professor
Homepage URL (1)： https://jp.linkedin.com/in/jun-nomura-2683273a?original_referer=https%3A%2F%2Fwww.google.com%2F

Research field (5)： Basic brain sciences , Biological, health, and medical informatics , Molecular biology , Psychiatry , Animals: biochemistry, physiology, behavioral science

Research keywords (8)：遺伝子工学 , Modeling , Tumorigenicity , Neuropsychiatric Disorders , Bioinformatics , Chromosome Engineering , Regenerative Medicine , Genome editing

Research theme for competitive and other funds (13)：

2024 - 2027 Phase-specific risk factor analysis of the translation process in autism
2021 - 2024 Identifying drug targets for neuropsychiatric and neurodevelopmental disorders via brain transcriptome
2018 - 2023 Integrated analysis of the human chromosome 15q13.3 copy number variation
2017 - 2020 Develop and analysis for chromosome mutant mice
2016 - 2017 RIKEN-MITI FS research fund

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Papers (39)：

Yoshiko Nomura*, Jun Nomura* (contributed equally), Kota Tamada*, Noriomi Eguchi, Kosuke Torigata, Shoichi Tokumoto, Akisa Nemoto, Toshihiko Shirafuji, Kana Yamamoto, Akitoyo Hishimoto, et al. Isogenic modeling of 1q21.1 reciprocal CNVs in human ES cells reveals divergent neurodevelopmental trajectories. Human Molecular Genetics. 2025
Kosuke Torigata, Jun Nomura, Toru Takumi. Single-cell transcriptome meta-analysis reveals epigenomic and chromatin dysregulation in developing neurons derived from human ESCs with 1q21.1 CNVs. Autism Research, in press. 2025
Jun Nomura, Amila Zuko, Keiko Kishimoto, Hiroaki Mutsumine, Hiroko Maegawa, Kazumi Fukatsu, Yoshiko Nomura, Xiaoxi Liu, Nobuhiro Nakai, ES Library team, et al. ESC models of autism with copy-number variations reveal cell-type-specific translational vulnerability. Cell Genomics. 2025. 5. 6. 1-16
Takatoshi Iijima, Yoko Hanno, Moe Nakanishi, Akinori Takase, Jun Nomura, Masami Tanaka, Yumi Iida, Masayuki Tanaka, Hiroyuki Hosokawa, Masatoshi Ito, et al. Targeting Notch Signaling to Restore Neural Development and Behavior in Autism. Research Square. 2025
Jacob Ellegood, Antoine Beauchamp, Yohan Yee, Gabe Devenyi, Justine Ziolkowski, Lily Qiu, Rand Askalan, Muhammad Ayub, Philipp Suetterlin, Alex Donovan, et al. Assigning Targetable Molecular Pathways to Transdiagnostic Subgroups Across Autism and Related Neurodevelopmental Disorders. BioRxiv. 2025

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MISC (31)：

Jun NOMURA. Identification of cell type-specific autism risk factors by single-cell, organoid studies. Japanese Journal of Biological Psychiatry. 2025. 36. 2. 56-60
Nomura J, Takumi T. Identification of cell type-specific autism risk factors by single-cell, organoid studies. Japanese Journal of Biological Psychiatry. 2022. 33. 2. 48-52
Jun Nomura, Toru Takumi. Emerging technologies for autism spectrum disorders. Japanese Journal of Biological Psychiatry. 2020. 31. 2. 71-75
Jun Nomura, Toru Takumi. Comprehensive analysis of the human chromosome 15q13.3 copy number variation. Smoking Research Foundation annual research report. 2019. 1132-1135
Jun Nomura, Toru Takumi. Trends in in vitro basic research for autism phenotyping. Journal of clinical and experimental medicine. 2019. 268. 3. 184-190

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Lectures and oral presentations (110)：

Elucidation of the Molecular Basis for Translation Abnormalities Common to Autism Spectrum Disorder
(The 48th Annual Meeting of the Molecular Biology Society of Japan 2025)
Cell-type specific pathology of microglia with autism-associated 1q21.1 copy number variations
(APPW2025 The 130th Annual Meeting of the Japanese Association of Anatomists (JAA) The 102nd Annual Meeting of the Physiological Society of Japan (PSJ) The 98th Annual Meeting of the Japanese Pharmacological Society (JPS) 2025)
The abnormal transcriptional network of TCF4 in the 15q13.3 microdeletion syndrome
(APPW2025 The 130th Annual Meeting of the Japanese Association of Anatomists (JAA) The 102nd Annual Meeting of the Physiological Society of Japan (PSJ) The 98th Annual Meeting of the Japanese Pharmacological Society (JPS) 2025)
【Symposium】Neuroscience@Kobe
(Symposium on Mental Disorders 2025)
Identification of key regulators of disease phenotypes associated with 15q13.3 deletion
(The 13th Japan Emotionology Society 2024)

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Education (3)：

2002 - 2005 Hokkaido University Graduate School of Pharmaceutical Sciences
1999 - 2001 Ritsumeikan University Graduate School of Science & Engineering
1995 - 1999 Ritsumeikan University Science & Engineering Environmental Systems Engineering

Professional career (1)：

Ph.D. (Pharmaceutical Sciences)

Work history (8)：

2025/04 - 現在 Kobe University Graduate School of Medicine Visiting Associate Professor
2024/04 - 2025/03 Kobe University Graduate School of Medicine Lecturer
2020/10 - 2024/03 Kobe University Graduate School of Medicine Assistant Professor
2020/04 - 2020/09 Kobe University Graduate School of Medicine Specially Appointed Assistant Professor
2016/04 - 2020/03 RIKEN Center for Brain Science Research Scientist

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Committee career (2)：

2018 - 現在 The International College of Neuropsychopharmacology (CINP) Fellow
2016 - 現在 The Japanese Society of Neuropsychopharmacology Councilor

Awards (6)：

2023 - Journal of Neurochemistry (Wiley) Top Downloaded Article in Journal of Neurochemistry Molecular signatures from multi-omics of autism spectrum disorders and schizophrenia
2022 - Neuroscience Research (Elsevier) Excellent Paper Award Transcriptome analysis of human neural cells derived from isogenic embryonic stem cells with 16p11.2 deletion.
2020/01 - Takeda Science Foundation, The 10th Takeda Science Foundation International Symposium on PharmaSciences Excellent Poster Award
2014 - RIKEN BSI Riken BSI Hot Topics 2014 Genome Editing Tools for Neurobiology
2009 - International Congress on Schizophrenia Research (ICOSR), Young Investigator Program Award 2009, USA, A new cell model to study the mechanism of gene-environment interactions relevant to schizophrenia

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Association Membership(s) (9)：

The Japanese Society for Bioinformatics , The Japanese Biochemical Society , The Molecular Biology Society of Japan , THE JAPANESE SOCIETY FOR NEUROCHEMISTRY , THE JAPAN NEUROSCIENCE SOCIETY , THE JAPANESE SOCIETY OF NEUROPSYCHOPHARMACOLOGY , International College of Neuropsychopharmacology , Society for Neuroscience , The International Behavioral Neuroscience Society (IBNS)

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